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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Katnb1
katanin p80 (WD40-containing) subunit B 1
MGI:1921437
45 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Katnb1taily/Katnb1taily
involves: C57BL/6 * CBA 		abnormal male meiosis J:185194
abnormal manchette disassembly J:185194
abnormal manchette morphology J:185194
abnormal manchette perinuclear ring morphology J:185194
abnormal meiotic spindle morphology J:185194
abnormal outer dense fiber morphology J:185194
abnormal sperm axoneme morphology J:185194
abnormal sperm flagellum morphology J:185194
abnormal spermatid morphology J:185194
absent sperm axonemal central pair J:185194
asthenozoospermia J:185194
decreased sperm progressive motility J:185194
elongated manchette J:185194
globozoospermia J:185194
increased Sertoli cell phagocytosis J:185194
male infertility J:185194
oligozoospermia J:185194
normal reproductive system phenotype J:185194
small testis J:185194
Katnb1tm1a(EUCOMM)Hmgu/Katnb1tm1a(EUCOMM)Hmgu
C57BL/6-Katnb1tm1a(EUCOMM)Hmgu 		abnormal cell cytoskeleton morphology J:220901
abnormal cell morphology J:220901
abnormal cortical ventricular zone morphology J:220901
abnormal embryo morphology J:220901
abnormal erythropoiesis J:220901
abnormal forebrain morphology J:220901
abnormal mitosis J:220901
abnormal mitotic spindle morphology J:220901
abnormal neuronal precursor proliferation J:220901
abnormal primary cilium morphology J:220901
aneuploidy J:220901
anophthalmia J:220901
binucleate J:220901
decreased brain size J:220901
decreased embryo size J:220901
decreased fibroblast proliferation J:220901
decreased neuronal precursor cell number J:220901
holoprosencephaly J:220901
increased brain apoptosis J:220901
lethality throughout fetal growth and development, complete penetrance J:220901
loss of cortex neurons J:220901
microphthalmia J:220901
pale liver J:220901
small limb buds J:220901
thin cerebral cortex J:220901
Katnb1tm1b(EUCOMM)Hmgu/Katnb1tm1b(EUCOMM)Hmgu
C57BL/6N-Katnb1tm1b(EUCOMM)Hmgu/H 		preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory