Tnks2 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
MGI:1921743

8 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnks2^tm1.1Susm/Tnks2⁺ involves: 129S/SvEv * C57BL/6	postnatal lethality, incomplete penetrance	J:106917
Tnks2^tm1.1Susm/Tnks2^tm1.1Susm involves: 129S/SvEv * C57BL/6	normal cellular phenotype	J:106917
	decreased body weight	J:106917
	postnatal lethality, incomplete penetrance	J:106917
Tnks2^tm1.1Yjc/Tnks2^tm1.1Yjc involves: 129S1/Sv	normal cellular phenotype	J:106918, J:137985
	decreased adipocyte glucose uptake	J:137985
	decreased body weight	J:106918, J:137985
	normal mortality/aging	J:106918
Tnks2^{tm1b(KOMP)Wtsi}/Tnks2^{tm1b(KOMP)Wtsi} C57BL/6N-Tnks2^{tm1b(KOMP)Wtsi}/J	abnormal coat/hair pigmentation	J:211773
	increased grip strength	J:211773
	increased startle reflex	J:211773
Tnks2^tm1Susm/Tnks2^tm1Susm involves: 129S/SvEv * C57BL/6	normal cellular phenotype	J:106917
	decreased body weight	J:106917
	postnatal lethality, incomplete penetrance	J:106917

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24