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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mgme1
mitochondrial genome maintenance exonuclease 1
MGI:1921778
13 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mgme1em1(IMPC)J/Mgme1em1(IMPC)J
C57BL/6NJ-Mgme1em1(IMPC)J/Mmjax 		abnormal coat/hair pigmentation J:211773
decreased total body fat amount J:211773
improved glucose tolerance J:211773
increased bone mineral content J:211773
increased fasting circulating glucose level J:211773
increased lean body mass J:211773
increased mean corpuscular hemoglobin J:211773
Mgme1tm1.1Lrsn/Mgme1tm1.1Lrsn
Tg(Ckmm-cre)5Khn/0
involves: C57BL/6NTac * FVB 		decreased mitochondrial DNA content J:259702
Mgme1tm1.2Lrsn/Mgme1tm1.2Lrsn
involves: C57BL/6NTac 		abnormal mitochondrial physiology J:259702
anemia J:259702
decreased hemoglobin content J:259702
decreased mitochondrial DNA content J:259702
normal growth/size/body region phenotype J:259702
normal reproductive system phenotype J:259702
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory