About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mlkl
mixed lineage kinase domain-like
MGI:1921818
11 phenotypes from 7 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mlklem1(IMPC)Ccpcz/Mlklem1(IMPC)Ccpcz
C57BL/6NCrl-Mlklem1(IMPC)Ccpcz/Ccpcz 		abnormal skin morphology J:211773
abnormal spleen morphology J:211773
enlarged spleen J:211773
Mlklem1Jhan/Mlklem1Jhan
involves: C57BL/6 		abnormal macrophage physiology J:204622
decreased sensitivity to induced cell death J:204622
decreased susceptibility to injury J:204622
normal immune system phenotype J:204622
normal mortality/aging J:204622
Mlklm1Btlr/Mlkl+
C57BL/6J-Mlklm1Btlr 		decreased cell death J:225934
decreased inflammatory response J:225934
Mlklm1Btlr/Mlklm1Btlr
C57BL/6J-Mlklm1Btlr 		decreased cell death J:225934
decreased inflammatory response J:225934
Mlklm2Btlr/Mlkl+
C57BL/6J-Mlklm2Btlr 		decreased cell death J:234252
decreased inflammatory response J:234252
Mlklm2Btlr/Mlklm2Btlr
C57BL/6J-Mlklm2Btlr 		decreased cell death J:234252
decreased inflammatory response J:234252
Mlklm3Btlr/Mlkl+
C57BL/6J-Mlklm3Btlr 		decreased cell death J:234251
decreased inflammatory response J:234251
Mlklm3Btlr/Mlklm3Btlr
C57BL/6J-Mlklm3Btlr 		decreased cell death J:234251
decreased inflammatory response J:234251
MlklM4Btlr/MlklM4Btlr
C57BL/6J-MlklM4Btlr 		decreased apoptosis J:272831
Mlkltm1.2Wsa/Mlkltm1.2Wsa
involves: BALB/cJ * C57BL/6 		decreased sensitivity to induced cell death J:204620
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory