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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stx11
syntaxin 11
MGI:1921982
34 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Stx11em1(IMPC)Mbp/Stx11em1(IMPC)Mbp
C57BL/6N-Stx11em1(IMPC)Mbp/MbpMmucd 		abnormal heart morphology J:211773
abnormal kidney morphology J:211773
enlarged heart J:211773
increased blood urea nitrogen level J:211773
increased heart weight J:211773
increased lymphocyte cell number J:211773
preweaning lethality, incomplete penetrance J:211773
small kidney J:211773
Stx11tm1.2Ics/Stx11tm1.2Ics
involves: C57BL/6NTac 		abnormal cytotoxic T cell physiology J:193137
decreased body temperature J:193137
decreased cytotoxic T cell cytolysis J:193137
decreased erythrocyte cell number J:193137
decreased leukocyte cell number J:193137
decreased neutrophil cell number J:193137
decreased NK cell degranulation J:193137
hunched posture J:193137
increased circulating aspartate transaminase level J:193137
increased circulating interferon-gamma level J:193137
increased circulating interleukin-1 beta level J:193137
increased circulating interleukin-6 level J:193137
increased circulating lactate dehydrogenase level J:193137
increased circulating tumor necrosis factor level J:193137
increased susceptibility to Riboviria infection J:193137
lethargy J:193137
pancytopenia J:193137
thrombocytopenia J:193137
weight loss J:193137
Stx11tm1Bupa/Stx11tm1Bupa
B6.129-Stx11tm1Bupa 		abnormal cell-mediated immunity J:191103
abnormal cytokine secretion J:191103
abnormal lymphocyte physiology J:191103
abnormal neutrophil physiology J:191103
impaired natural killer cell mediated cytotoxicity J:191103
increased interferon-gamma secretion J:191103
increased tumor necrosis factor secretion J:191103
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory