Dhcr24 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dhcr24
24-dehydrocholesterol reductase
MGI:1922004

19 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dhcr24^{tm1a(EUCOMM)Wtsi}/Dhcr24⁺ B6JTyr;B6N-Dhcr24^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal behavior	J:175295
	decreased circulating triglyceride level	J:175295
Dhcr24^{tm1a(EUCOMM)Wtsi}/Dhcr24^{tm1a(EUCOMM)Wtsi} B6Brd;B6N-Tyr^c-Brd Dhcr24^{tm1a(EUCOMM)Wtsi}/WtsiCnbc	prenatal lethality, complete penetrance	J:304449
Dhcr24^{tm1c(EUCOMM)Wtsi}/Dhcr24^{tm1c(EUCOMM)Wtsi} Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J * C57BL/6N	abnormal bile composition	J:304449
	abnormal sterol level	J:304449
	decreased circulating cholesterol level	J:304449
Dhcr24^{tm1c(EUCOMM)Wtsi}/Dhcr24^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ B6.Cg-Dhcr24^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}	abnormal bile composition	J:304449
	abnormal feces composition	J:304449
	abnormal liver morphology	J:304449
	abnormal sterol level	J:304449
	decreased liver cholesterol level	J:304449
Dhcr24^tm1Lex/Dhcr24^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal circulating cholesterol level	J:87402
	abnormal mesenteric fat pad morphology	J:87402
	decreased body size	J:87402
	decreased body weight	J:87402
	decreased circulating cholesterol level	J:87402
	decreased subcutaneous adipose tissue amount	J:87402
	female infertility	J:87402
	male infertility	J:87402
	postnatal growth retardation	J:87402
	prenatal lethality, incomplete penetrance	J:87402
	testis degeneration	J:87402

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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