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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
MGI:1922019
9 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pik3catm1Jjz/Pik3catm1Jjz
Pik3cbtm1Jjz/Pik3cbtm1Jjz
Ptentm1Hwu/Ptentm1Hwu
Tg(KRT14-cre)#Smr/0
FVB.Cg-Pik3catm1Jjz Pik3cbtm1Jjz Ptentm1Hwu Tg(KRT14-cre)#Smr 		normal integument phenotype J:199362
Pik3catm1Nbm/Pik3ca+
Pik3cbtm1Nbm/Pik3cb+
involves: 129S6/SvEvTac 		impaired glucose tolerance J:96761
increased circulating insulin level J:96761
Pik3cbtm1.1Ehi/Pik3cbtm1.1Ehi
Tg(MMTVneu)202Mul/0
involves: 129/Sv * 129P2/OlaHsd * BALB/c * C57BL/6J * FVB/N 		decreased mammary gland tumor incidence J:152332
decreased tumor growth/size J:152332
Pik3cbtm1Jjz/Pik3cbtm1Jjz
Ptentm1Hwu/Ptentm1Hwu
Tg(KRT14-cre)#Smr/0
FVB.Cg-Pik3cbtm1Jjz Ptentm1Hwu Tg(KRT14-cre)#Smr 		abnormal epidermis suprabasal layer morphology J:199362
increased skin hamartoma incidence J:199362
skin lesions J:199362
thick skin J:199362
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory