Miga2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Miga2
mitoguardin 2
MGI:1922035

36 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Miga2^{tm1a(KOMP)Wtsi}/Miga2^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Miga2^{tm1a(KOMP)Wtsi}/Wtsi	abnormal behavior	J:175295
	abnormal cranium morphology	J:175295
	abnormal maxilla morphology	J:175295
	abnormal snout morphology	J:175295
	abnormal tooth morphology	J:175295
	decreased body length	J:175295
	decreased body weight	J:175295
	decreased bone mineral content	J:175295
	decreased bone mineral density	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased circulating cholesterol level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	decreased circulating LDL cholesterol level	J:175295
	decreased circulating serum albumin level	J:175295
	decreased circulating total protein level	J:175295
	decreased hematocrit	J:175295
	decreased hemoglobin content	J:175295
	decreased lactate dehydrogenase level	J:175295
	decreased lean body mass	J:175295
	decreased total body fat amount	J:175295
	hyperactivity	J:175295
Miga2^{tm1a(KOMP)Wtsi}/Miga2^{tm1a(KOMP)Wtsi} C57BL/6N-Miga2^{tm1a(KOMP)Wtsi}/Mmucd	abnormal CD4-positive, alpha beta T cell morphology	J:339075
	decreased social novelty preference	J:339075
	increased anxiety-related response	J:339075
	increased depression-related behavior	J:339075
	increased thigmotaxis	J:339075
Miga2^{tm1c(KOMP)Wtsi}/Miga2^{tm1c(KOMP)Wtsi} Tg(Cd4-cre)1Cwi/0 B6.Cg-Miga2^{tm1c(KOMP)Wtsi} Tg(Cd4-cre)1Cwi	abnormal amygdala morphology	J:339075
	abnormal blood homeostasis	J:339075
	abnormal brain morphology	J:339075
	abnormal CD4-positive, alpha-beta T cell physiology	J:339075
	abnormal immune system morphology	J:339075
	normal immune system phenotype	J:339075
	increased amino acid level	J:339075
	increased amygdala size	J:339075
	increased anxiety-related response	J:339075
	increased circulating hypoxanthine level	J:339075
	increased circulating xanthine level	J:339075
	increased thigmotaxis	J:339075

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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