Asxl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Asxl2
ASXL transcriptional regulator 2
MGI:1922552

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Asxl2^{Gt(AQ0356)Wtsi}/Asxl2^{Gt(AQ0356)Wtsi} involves: 129P2/OlaHsd * C57BL/6J	abnormal heart morphology	J:147372
	abnormal sacral vertebrae morphology	J:147372
	cardiac interstitial fibrosis	J:147372
	decreased body weight	J:147372
	enlarged heart	J:147372
	lethargy	J:147372
	lumbar vertebral transformation	J:147372
	postnatal growth retardation	J:147372
	postnatal lethality, incomplete penetrance	J:147372
	premature death	J:147372
	prenatal lethality, incomplete penetrance	J:147372
	sacral vertebral transformation	J:147372
	split vertebrae	J:147372
	thoracic vertebral transformation	J:147372
Asxl2^{tm1b(EUCOMM)Hmgu}/Asxl2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Asxl2^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal retina morphology	J:211773
	decreased mean corpuscular volume	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating cholesterol level	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	prolonged QRS complex duration	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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