Secisbp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Secisbp2
SECIS binding protein 2
MGI:1922670

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ Secisbp2^tm1.1Amdu/Secisbp2^tm1.2Amdu B6(129S4)-Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj} Secisbp2^tm1.1Amdu Secisbp2^tm1.2Amdu	abnormal enzyme/coenzyme activity	J:251875
	abnormal pituitary gland physiology	J:251875
	abnormal thyroid hormone level	J:251875
	decreased body weight	J:251875
	decreased triiodothyronine level	J:251875
	increased circulating thyroid-stimulating hormone level	J:251875
	increased thyroxine level	J:251875
	infertility	J:251875
	premature death	J:251875
Secisbp2^tm1.2Amdu/Secisbp2^tm1.2Amdu B6(129S4)-Secisbp2^tm1.2Amdu	prenatal lethality, complete penetrance	J:251875
Secisbp2^{tm1a(EUCOMM)Wtsi}/Secisbp2⁺ involves: C57BL/6N	abnormal selenium level	J:213080
	normal homeostasis/metabolism phenotype	J:213080
	normal reproductive system phenotype	J:213080
Secisbp2^{tm1a(EUCOMM)Wtsi}/Secisbp2⁺ Not Specified	increased NK cell number	J:165965
Secisbp2^{tm1a(EUCOMM)Wtsi}/Secisbp2^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	embryonic growth arrest	J:213080
	embryonic growth retardation	J:213080
	embryonic lethality between implantation and placentation, incomplete penetrance	J:213080
	embryonic lethality during organogenesis, incomplete penetrance	J:213080
	preweaning lethality, complete penetrance	J:213080
Secisbp2^{tm1c(EUCOMM)Wtsi}/Secisbp2^{tm1c(EUCOMM)Wtsi} C57BL/6N-Secisbp2^{tm1a(EUCOMM)Wtsi}/H	abnormal retina morphology	J:211773
	increased leukocyte cell number	J:211773
Secisbp2^{tm1c(EUCOMM)Wtsi}/Secisbp2^{tm1c(EUCOMM)Wtsi} Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * C57BL/6N * DBA	normal liver/biliary system phenotype	J:213080
Secisbp2^{tm1d(EUCOMM)Wtsi}/Secisbp2^{tm1d(EUCOMM)Wtsi} involves: C57BL/6N	preweaning lethality, complete penetrance	J:213080

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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