About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nhej1
non-homologous end joining factor 1
MGI:1922820
15 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Nhej1tm1.1Ics/Nhej1+
involves: 129 * C57BL/6 		decreased thymocyte number J:194422
Nhej1tm1.1Ics/Nhej1tm1.1Ics
involves: 129 * C57BL/6 		abnormal T cell receptor V(D)J recombination J:194422
decreased lymphocyte cell number J:194422
decreased NK T cell number J:194422
decreased thymocyte number J:194422
increased sensitivity to induced cell death J:194422
increased thymocyte apoptosis J:194422
Nhej1tm1Fwa/Nhej1tm1Fwa
129S6/SvEvTac-Nhej1tm1Fwa 		abnormal DNA repair J:120145
increased cellular sensitivity to gamma-irradiation J:120145
spontaneous chromosome breakage J:120145
Nhej1tm1Fwa/Nhej1tm1Fwa
involves: 129 		abnormal class switch recombination J:138774
decreased IgG1 level J:138774
decreased IgG3 level J:138774
increased cellular sensitivity to gamma-irradiation J:138774
increased IgM level J:138774
spleen hypoplasia J:138774
spontaneous chromosome breakage J:138774
thymus hypoplasia J:138774
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory