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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fads1
fatty acid desaturase 1
MGI:1923517
25 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fads1Gt(IST11525H2)Tigm/Fads1+
C57BL/6-Fads1Gt(IST11525H2)Tigm 		abnormal enterocyte proliferation J:186265
decreased interferon-gamma secretion J:186265
decreased prostaglandin level J:186265
decreased tumor necrosis factor secretion J:186265
increased prostaglandin level J:186265
Fads1Gt(IST11525H2)Tigm/Fads1Gt(IST11525H2)Tigm
C57BL/6-Fads1Gt(IST11525H2)Tigm 		abnormal circulating lipid level J:186265
abnormal enterocyte proliferation J:186265
abnormal lipid level J:186265
abnormal mononuclear cell morphology J:186265
decreased interferon-gamma secretion J:186265
decreased prostaglandin level J:186265
decreased regulatory T cell number J:186265
decreased tumor necrosis factor secretion J:186265
increased prostaglandin level J:186265
increased susceptibility to xenobiotic induced morbidity/mortality J:186265
premature death J:186265
Fads1tm1.1(KOMP)Vlcg/Fads1tm1.1(KOMP)Vlcg
C57BL/6N-Fads1tm1.1(KOMP)Vlcg/Ucd 		abnormal testis morphology J:211773
decreased circulating cholesterol level J:211773
decreased circulating triglyceride level J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased total body fat amount J:211773
improved glucose tolerance J:211773
increased bone mineral content J:211773
increased brain weight J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating phosphate level J:211773
increased kidney weight J:211773
preweaning lethality, incomplete penetrance J:211773
small testis J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory