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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Wdr62
WD repeat domain 62
MGI:1923696
42 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Wdr62em1(IMPC)Tcp/Wdr62em1(IMPC)Tcp
C57BL/6NCrl-Wdr62em1(IMPC)Tcp/Tcp 		decreased prepulse inhibition J:211773
enlarged lymph nodes J:211773
increased circulating sodium level J:211773
male infertility J:211773
microphthalmia J:211773
small kidney J:211773
small seminal vesicle J:211773
small testis J:211773
Wdr62Gt(AF0003)Wtsi/Wdr62Gt(AF0003)Wtsi
involves: 129P2/OlaHsd * 129S1/SvImJ 		abnormal mitosis J:224504
abnormal mitotic spindle assembly checkpoint J:224504
abnormal mitotic spindle morphology J:224504
abnormal nervous system physiology J:224504
decreased neuronal precursor cell number J:224504
fetal growth retardation J:224504
increased cell death J:224504
loss of cortex neurons J:224504
microcephaly J:224504
proportional dwarf J:224504
reduced fertility J:224504
thin cerebral cortex J:224504
Wdr62tm1.1Jfch/Wdr62tm1.1Jfch
involves: 129S1/SvImJ * C57BL/6N 		abnormal cell cycle J:282438
abnormal neocortex size J:282438
abnormal primary cilium morphology J:282438
decreased brain size J:282438
decreased brain weight J:282438
decreased cell proliferation J:282438
decreased neuronal precursor cell number J:282438
increased forebrain apoptosis J:282438
premature neuronal precursor differentiation J:282438
Wdr62tm3a(EUCOMM)Hmgu/Wdr62tm3a(EUCOMM)Hmgu
C57BL/6-Wdr62tm3a(EUCOMM)Hmgu 		abnormal cortical ventricular zone morphology J:306320
abnormal male meiosis J:306320
abnormal manchette disassembly J:306320
abnormal neocortex morphology J:306320
abnormal seminiferous tubule morphology J:306320
abnormal sperm head morphology J:306320
absent oocytes J:306320
asthenozoospermia J:306320
decreased sperm progressive motility J:306320
decreased testis weight J:306320
female infertility J:306320
normal growth/size/body region phenotype J:306320
male infertility J:306320
oligozoospermia J:306320
small testis J:306320
teratozoospermia J:306320
thin cerebral cortex J:306320
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory