Ccdc6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccdc6
coiled-coil domain containing 6
MGI:1923801

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccdc6^{em1(IMPC)Wtsi}/Ccdc6^{em1(IMPC)Wtsi} C57BL/6N-Ccdc6^{em1(IMPC)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Ccdc6^tm1Afus/Ccdc6^tm1Afus involves: 129 * C57BL/6J	abnormal cell cycle	J:301625
	decreased fibroblast proliferation	J:301625
	decreased thyroid-stimulating hormone level	J:301625
	increased cellular sensitivity to hydrogen peroxide	J:301625
	increased fibroblast apoptosis	J:301625
	increased thyroxine level	J:301625
	increased triiodothyronine level	J:301625
	prenatal lethality, incomplete penetrance	J:301625
	thyroid gland hyperplasia	J:301625

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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