Gins4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gins4
GINS complex subunit 4
MGI:1923847

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gins4^{tm1b(EUCOMM)Hmgu}/Gins4⁺ C57BL/6N-Gins4^{tm1b(EUCOMM)Hmgu}/Bay	abnormal retina morphology	J:211773
	abnormal retina outer nuclear layer morphology	J:211773
	decreased total retina thickness	J:211773
	increased startle reflex	J:211773
	microphthalmia	J:211773
Gins4^{tm1b(EUCOMM)Hmgu}/Gins4^{tm1b(EUCOMM)Hmgu} C57BL/6N-Gins4^{tm1b(EUCOMM)Hmgu}/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Gins4^tm1Ntak/Gins4^tm1Ntak involves: 129P2/OlaHsd * C57BL/6	decreased inner cell mass proliferation	J:209708
	embryonic lethality between implantation and somite formation, complete penetrance	J:209708
	increased inner cell mass apoptosis	J:209708

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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