Immt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Immt
inner membrane protein, mitochondrial
MGI:1923864

37 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Immt^{Gt(AW0256)Wtsi}/Immt⁺ involves: 129P2/OlaHsd	abnormal carbohydrate metabolism	J:344896
	abnormal gait	J:344896
	abnormal mitochondrial ATP synthesis coupled electron transport	J:344896
	abnormal mitochondrial crista morphology	J:344896
	abnormal mitochondrial matrix morphology	J:344896
	abnormal mitochondrial physiology	J:344896
	abnormal motor capabilities/coordination/movement	J:344896
	abnormal muscle fiber mitochondrial morphology	J:344896
	abnormal neuron mitochondrial morphology	J:344896
	abnormal oxidative phosphorylation	J:344896
	decreased carbon dioxide production	J:344896
	decreased dopaminergic neuron number	J:344896
	decreased hippocampus volume	J:344896
	decreased oxygen consumption	J:344896
	decreased Purkinje cell number	J:344896
	decreased respiratory quotient	J:344896
	enlarged lateral ventricles	J:344896
	impaired coordination	J:344896
	impaired spatial learning	J:344896
	increased carbon dioxide production	J:344896
	increased cellular glucose import	J:344896
	increased cellular sensitivity to X-ray irradiation	J:344896
	increased circulating creatine kinase level	J:344896
	increased circulating glucose level	J:344896
	increased circulating lactate dehydrogenase level	J:344896
	increased circulating lactate level	J:344896
	increased neuron apoptosis	J:344896
	increased oxygen consumption	J:344896
	increased respiratory quotient	J:344896
	neurofibrillary tangles	J:344896
	oxidative stress	J:344896
	short stride length	J:344896
	small cerebellum	J:344896
Immt^{Gt(AW0256)Wtsi}/Immt^{Gt(AW0256)Wtsi} involves: 129P2/OlaHsd	abnormal embryo morphology	J:344896
	decreased embryo size	J:344896
	embryonic lethality during organogenesis, complete penetrance	J:344896
	increased embryonic tissue cell apoptosis	J:344896

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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