Kansl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kansl1
KAT8 regulatory NSL complex subunit 1
MGI:1923969

22 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kansl1^em1.1Cya/Kansl1⁺ B6(FVB)-Kansl1^em1.1Cya	abnormal autophagy	J:327464
	abnormal heart echocardiography feature	J:327464
	decreased cardiac muscle contractility	J:327464
	decreased dendritic spine density	J:327464
	impaired long-term object recognition memory	J:327464
	impaired spatial learning	J:327464
	oxidative stress	J:327464
Kansl1^em1.1Cya/Kansl1^em1.1Cya B6(FVB)-Kansl1^em1.1Cya	abnormal autophagy	J:327464
Kansl1^em1.1Cya/Kansl1^em1.1Cya B6(FVB)-Kansl1^em1.1Cya	prenatal lethality, complete penetrance	J:327464
Kansl1^em1Cya/Kansl1⁺ Tg(CAG-cre/Esr1*)5Amc/0 Not Specified	abnormal autophagy	J:327464
Kansl1^em1Cya/Kansl1^em1Cya Tg(CAG-cre/Esr1)5Amc/0 B6.Cg-Kansl1^em1Cya Tg(CAG-cre/Esr1)5Amc	abnormal autophagy	J:327464
	abnormal mitophagy	J:327464
	abnormal neuron mitochondrial morphology	J:327464
	abnormal neuron physiology	J:327464
	oxidative stress	J:327464
Kansl1^{tm1b(EUCOMM)Hmgu}/Kansl1⁺ involves: C57BL/6N	abnormal locomotor circadian rhythm	J:244312
	abnormal motor learning	J:244312
	normal behavior/neurological phenotype	J:244312
	decreased body size	J:244312
	decreased body weight	J:244312
	decreased stereotypic behavior	J:244312
	decreased total body fat amount	J:244312
	enhanced coordination	J:244312
	impaired contextual conditioning behavior	J:244312
	impaired cued conditioning behavior	J:244312
	impaired long-term object recognition memory	J:244312
	increased vertical activity	J:244312

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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