Pbrm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pbrm1
polybromo 1
MGI:1923998

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pbrm1^{tm1b(EUCOMM)Wtsi}/Pbrm1⁺ C57BL/6N-Pbrm1^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal gait	J:211773
	abnormal kidney morphology	J:211773
	decreased circulating creatinine level	J:211773
	decreased prepulse inhibition	J:211773
	increased mean platelet volume	J:211773
Pbrm1^{tm1b(EUCOMM)Wtsi}/Pbrm1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Pbrm1^{tm1b(EUCOMM)Wtsi}/Ieg	preweaning lethality, complete penetrance	J:211773
Pbrm1^tm1Rtj/Pbrm1^tm1Rtj Not Specified	abnormal interventricular septum morphology	J:95332
	abnormal placenta labyrinth morphology	J:95332
	abnormal spongiotrophoblast layer morphology	J:95332
	abnormal trophoblast giant cell morphology	J:95332
	lethality throughout fetal growth and development, complete penetrance	J:95332
	small liver	J:95332
	small lung	J:95332
	ventricular hypoplasia	J:95332
Pbrm1^tm1Zhwa/Pbrm1^tm1Zhwa Tg(Cd4-cre)1Cwi/? involves: 129P2/OlaHsd * C57BL/6 * DBA/2	abnormal T-helper 2 cell differentiation	J:236906
	decreased T cell proliferation	J:236906
	normal immune system phenotype	J:236906
	increased interleukin-4 secretion	J:236906
	increased interleukin-10 secretion	J:236906

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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