Rhbdd1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rhbdd1
rhomboid domain containing 1
MGI:1924117

9 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Rhbdd1^tm1.1Mfm/Rhbdd1^tm1.1Mfm involves: 129S/SvEv * C57BL/6J	abnormal endoplasmic reticulum morphology	J:325547
	abnormal protein level	J:346394
	increased endoplasmic reticulum stress	J:325547
	increased interleukin-6 secretion	J:346394
	increased susceptibility to endotoxin shock	J:346394
	increased susceptibility to hepatic steatosis	J:325547
	increased susceptibility to weight loss	J:325547
	increased susceptibility to xenobiotic induced morbidity/mortality	J:346394
	increased tumor necrosis factor secretion	J:346394

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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