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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rdh10
retinol dehydrogenase 10 (all-trans)
MGI:1924238
124 phenotypes from 8 alleles in 13 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
involves: 129S4/SvJae * C57BL/6N * FVB/NJ 		abnormal spontaneous fetal mouth movement J:278485
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1d(KOMP)Wtsi
involves: 129S4/SvJae * C57BL/6N * FVB/NJ 		abnormal cricoid cartilage morphology J:278485
abnormal hyoid bone morphology J:278485
abnormal hypoglossal nerve morphology J:278485
abnormal motor neuron morphology J:278485
abnormal palatal shelf elevation J:278485
abnormal thyroid cartilage morphology J:278485
abnormal tongue muscle morphology J:278485
abnormal tongue position J:278485
cleft secondary palate J:278485
normal craniofacial phenotype J:278485
decreased palatine bone horizontal plate size J:278485
decreased tongue size J:278485
palatal shelves fail to meet at midline J:278485
Rdh10m366Asp/Rdh10m366Asp
involves: C57BL/6J 		abnormal cerebral cortex morphology J:157301
abnormal craniofacial morphology J:157301
abnormal eye morphology J:157301
abnormal forebrain morphology J:157301
abnormal limb morphology J:157301
normal nervous system phenotype J:157301
Rdh10m366Asp/Rdh10m366Asp
Tg(Rr291-lacZ)#Mekk/0
involves: C57BL/6J * FVB/N 		thin cerebral cortex J:136795
Rdh10tm1.1Ics/Rdh10tm1.1Ics
involves: C57BL/6 * SJL 		abnormal cardiovascular system physiology J:177362
abnormal craniofacial development J:177362
abnormal embryo development J:177362
abnormal eye development J:177362
abnormal heart development J:177362
abnormal heart tube morphology J:177362
abnormal hindbrain development J:177362
abnormal intestine morphology J:177362
abnormal limb morphology J:177362
abnormal mesoderm development J:177362
abnormal otic vesicle morphology J:177362
abnormal pharyngeal arch morphology J:177362
abnormal stomach morphology J:177362
absent lungs J:177362
brachydactyly J:177362
caudal body truncation J:177362
circling J:177362
decreased ventral retina size J:177362
normal embryo phenotype J:177362
embryo tissue necrosis J:177362
embryonic growth retardation J:177362
embryonic lethality during organogenesis, complete penetrance J:177362
facial cleft J:177362
incomplete embryo turning J:177362
lethality during fetal growth through weaning, complete penetrance J:177362
liver hypoplasia J:177362
pancreas hypoplasia J:177362
persistent truncus arteriosus J:177362
renal hypoplasia J:177362
small forelimb buds J:177362
small lens J:177362
small otic vesicle J:177362
syndactyly J:177362
Rdh10tm1a(KOMP)Wtsi/Rdh10tm1a(KOMP)Wtsi
involves: C57BL/6J * C57BL/6N 		abnormal embryo turning J:185330
abnormal heart tube morphology J:185330
abnormal rostral-caudal body axis extension J:185330
absent pharyngeal arches J:185330
decreased embryo size J:185330
decreased somite size J:185330
embryonic growth retardation J:185330
failure of heart looping J:185330
small otic vesicle J:185330
Rdh10tm1a(KOMP)Wtsi/Rdh10trex
involves: 129S1/Sv * C57BL/6J * C57BL/6N 		abnormal embryonic tissue morphology J:185330
decreased embryo size J:185330
decreased somite size J:185330
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
Tg(Amh-cre)8815Reb/0
involves: C57BL/6 * C57BL/6N * FVB/N * SJL 		abnormal male reproductive system physiology J:193281
decreased testis weight J:193281
seminiferous tubule degeneration J:193281
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
Tg(Amh-cre)8815Reb/0
Tg(RARE-Hspa1b/lacZ)12Jrt/0
Tg(Stra8-icre)1Reb/0
involves: C57BL/6 * C57BL/6N * CD-1 * FVB/N * SJL 		abnormal male reproductive system physiology J:193281
small testis J:193281
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
Tg(Amh-cre)8815Reb/0
Tg(Stra8-icre)1Reb/0
involves: C57BL/6 * C57BL/6N * FVB/N * SJL 		abnormal male reproductive system physiology J:193281
abnormal seminiferous tubule morphology J:193281
abnormal spermatogenesis J:193281
abnormal spermatogonia morphology J:193281
arrest of male meiosis J:193281
decreased testis weight J:193281
reduced male fertility J:193281
seminiferous tubule degeneration J:193281
small testis J:193281
Rdh10tm1c(KOMP)Wtsi/Rdh10tm1c(KOMP)Wtsi
Tg(Stra8-icre)1Reb/0
involves: C57BL/6 * C57BL/6N * FVB/NJ * SJL 		normal reproductive system phenotype J:193281
Rdh10tm1d(KOMP)Wtsi/Rdh10tm1d(KOMP)Wtsi
involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N 		abnormal embryo turning J:185330
abnormal heart tube morphology J:185330
abnormal vitamin A metabolism J:185330
decreased embryo size J:185330
decreased somite size J:185330
embryonic growth arrest J:185330
embryonic growth retardation J:185330
embryonic lethality during organogenesis, complete penetrance J:185330
failure of heart looping J:185330
small otic vesicle J:185330
Rdh10tm1Ics/Rdh10tm1Ics
Not Specified 		no abnormal phenotype detected J:177362
Rdh10tm2Ics/Rdh10tm2Ics
Not Specified 		abnormal cardiovascular system physiology J:177362
abnormal craniofacial development J:177362
abnormal embryo development J:177362
abnormal eye development J:177362
abnormal heart development J:177362
abnormal heart tube morphology J:177362
abnormal hindbrain development J:177362
abnormal intestine morphology J:177362
abnormal limb morphology J:177362
abnormal mesoderm development J:177362
abnormal otic vesicle morphology J:177362
abnormal pharyngeal arch morphology J:177362
abnormal stomach morphology J:177362
absent lungs J:177362
brachydactyly J:177362
caudal body truncation J:177362
circling J:177362
decreased ventral retina size J:177362
normal embryo phenotype J:177362
embryo tissue necrosis J:177362
embryonic growth retardation J:177362
embryonic lethality during organogenesis, complete penetrance J:177362
facial cleft J:177362
incomplete embryo turning J:177362
lethality during fetal growth through weaning, complete penetrance J:177362
liver hypoplasia J:177362
pancreas hypoplasia J:177362
persistent truncus arteriosus J:177362
renal hypoplasia J:177362
small forelimb buds J:177362
small lens J:177362
small otic vesicle J:177362
syndactyly J:177362
Rdh10trex/Rdh10trex
involves: 129S1/Sv * C57BL/6 		abnormal fourth pharyngeal arch morphology J:185330
abnormal heart looping J:185330
abnormal otic vesicle morphology J:185330
abnormal pharyngeal arch morphology J:185330
abnormal sixth pharyngeal arch morphology J:185330
abnormal third pharyngeal arch morphology J:185330
abnormal vitamin A metabolism J:185330
absent fourth pharyngeal arch J:185330
absent pharyngeal arches J:185330
absent sixth pharyngeal arch J:185330
absent third pharyngeal arch J:185330
cardiac edema J:185330
fused pharyngeal arches J:185330
small forelimb buds J:185330
small otic vesicle J:185330
Rdh10trex/Rdh10trex
involves: 129S1/Sv * C57BL/6 * FVB/NJ 		abnormal cardiac outflow tract development J:171522
abnormal cranial ganglia morphology J:121229, J:171522
abnormal craniofacial morphology J:121229
abnormal digit development J:121229
abnormal dorsal aorta morphology J:171522
abnormal eye development J:121229, J:171522
abnormal forelimb bud morphology J:121229
abnormal forelimb morphology J:121229
abnormal frontonasal prominence morphology J:121229
abnormal geniculate ganglion morphology J:121229, J:171522
abnormal glossopharyngeal ganglion morphology J:121229, J:171522
abnormal lateral nasal prominence morphology J:171522
abnormal liver parenchyma morphology J:121229
abnormal lung development J:121229
abnormal maxillary prominence morphology J:171522
abnormal medial nasal prominence morphology J:171522
abnormal metanephros morphology J:121229
abnormal midgut morphology J:121229
abnormal nasal placode morphology J:171522
abnormal optic vesicle formation J:121229, J:171522
abnormal otic vesicle development J:171522
abnormal otic vesicle morphology J:121229
abnormal pharyngeal arch morphology J:171522
abnormal reproductive system development J:121229
abnormal retina morphology J:121229
abnormal second pharyngeal arch artery morphology J:171522
abnormal third pharyngeal arch morphology J:171522
abnormal trigeminal ganglion morphology J:121229, J:171522
abnormal vagus ganglion morphology J:171522
abnormal vestibulocochlear ganglion morphology J:121229, J:171522
absent cornea J:121229
absent fourth pharyngeal arch J:171522
absent lung buds J:121229
absent nasal cavity J:121229
absent nasal septum J:121229
absent pancreas J:121229
absent pharyngeal arches J:121229
absent radius J:121229
absent sixth pharyngeal arch artery J:171522
absent third pharyngeal arch artery J:171522
decreased autopod size J:121229
normal embryo phenotype J:121229
embryonic lethality during organogenesis, complete penetrance J:121229, J:171522
facial cleft J:121229
frontonasal prominence hypoplasia J:171522
fused pharyngeal arches J:171522
hemorrhage J:121229
impaired branching involved in trachea morphogenesis J:121229
midline facial cleft J:171522
pulmonary hypoplasia J:121229
small gonad J:121229
small lens J:121229
small liver J:121229
small otic vesicle J:121229
small stomach J:121229
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory