Slc9a8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc9a8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
MGI:1924281

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc9a8^{Gt(YHB273)Byg}/Slc9a8^{Gt(YHB273)Byg} involves: 129P2/OlaHsd * Black Swiss	abnormal blood coagulation	J:191151
	abnormal cecum morphology	J:191151
	abnormal colon goblet cell morphology	J:191151
	abnormal ileum crypts of Lieberkuhn morphology	J:191151
	abnormal intestinal mucosa morphology	J:191151
	abnormal small intestine morphology	J:191151
	decreased circulating bicarbonate level	J:191151
	male infertility	J:191151
Slc9a8^m1Btlr/Slc9a8^m1Btlr C57BL/6J-Slc9a8^m1Btlr	increased susceptibility to induced colitis	J:267481
Slc9a8^{tm1a(KOMP)Wtsi}/Slc9a8^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Slc9a8^{tm1a(KOMP)Wtsi}/Wtsi	abnormal eye morphology	J:175295
	abnormal retina morphology	J:175295
	abnormal retina pigmentation	J:175295
Slc9a8^{tm1c(KOMP)Wtsi}/Slc9a8^{tm1c(KOMP)Wtsi} Tg(Amh-cre)8815Reb/0 involves: C57BL/6N	normal reproductive system phenotype	J:245977
Slc9a8^{tm1c(KOMP)Wtsi}/Slc9a8^{tm1c(KOMP)Wtsi} Tg(Stra8-icre)1Reb/0 involves: C57BL/6J * C57BL/6N * FVB/NJ	abnormal acrosome assembly	J:245977
	abnormal proacrosomal vesicle fusion	J:245977
	abnormal sperm head morphology	J:245977
	abnormal sperm mitochondrial sheath morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977
	globozoospermia	J:245977
	male infertility	J:245977
	normal reproductive system phenotype	J:245977
Slc9a8^{tm1d(KOMP)Wtsi}/Slc9a8^{tm1d(KOMP)Wtsi} involves: C57BL/6N	abnormal acrosome assembly	J:245977
	abnormal proacrosomal vesicle fusion	J:245977
	abnormal sperm mitochondrial sheath morphology	J:245977
	abnormal sperm nucleus morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977
	asthenozoospermia	J:245977
	globozoospermia	J:245977
	male infertility	J:245977
	normal reproductive system phenotype	J:245977
Slc9a8^{tm1d(KOMP)Wtsi}/Slc9a8^{tm1d(KOMP)Wtsi} Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0 involves: C57BL/6 * C57BL/6N * DBA/2	abnormal sperm mitochondrial sheath morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24