Slc9a8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc9a8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
MGI:1924281

22 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc9a8^{Gt(YHB273)Byg}/Slc9a8^{Gt(YHB273)Byg} involves: 129P2/OlaHsd * Black Swiss	abnormal blood coagulation	J:191151
	abnormal cecum morphology	J:191151
	abnormal colon goblet cell morphology	J:191151
	abnormal ileum crypts of Lieberkuhn morphology	J:191151
	abnormal intestinal mucosa morphology	J:191151
	abnormal small intestine morphology	J:191151
	decreased circulating bicarbonate level	J:191151
	male infertility	J:191151
Slc9a8^m1Btlr/Slc9a8^m1Btlr C57BL/6J-Slc9a8^m1Btlr	increased susceptibility to induced colitis	J:267481
Slc9a8^{tm1a(KOMP)Wtsi}/Slc9a8^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Slc9a8^{tm1a(KOMP)Wtsi}/Wtsi	abnormal eye morphology	J:175295
	abnormal retina morphology	J:175295
	abnormal retina pigmentation	J:175295
Slc9a8^{tm1c(KOMP)Wtsi}/Slc9a8^{tm1c(KOMP)Wtsi} Tg(Amh-cre)8815Reb/0 involves: C57BL/6N	normal reproductive system phenotype	J:245977
Slc9a8^{tm1c(KOMP)Wtsi}/Slc9a8^{tm1c(KOMP)Wtsi} Tg(Stra8-icre)1Reb/0 involves: C57BL/6J * C57BL/6N * FVB/NJ	abnormal acrosome assembly	J:245977
	abnormal proacrosomal vesicle fusion	J:245977
	abnormal sperm head morphology	J:245977
	abnormal sperm mitochondrial sheath morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977
	globozoospermia	J:245977
	male infertility	J:245977
	normal reproductive system phenotype	J:245977
Slc9a8^{tm1d(KOMP)Wtsi}/Slc9a8^{tm1d(KOMP)Wtsi} involves: C57BL/6N	abnormal acrosome assembly	J:245977
	abnormal proacrosomal vesicle fusion	J:245977
	abnormal sperm mitochondrial sheath morphology	J:245977
	abnormal sperm nucleus morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977
	asthenozoospermia	J:245977
	globozoospermia	J:245977
	male infertility	J:245977
	normal reproductive system phenotype	J:245977
Slc9a8^{tm1d(KOMP)Wtsi}/Slc9a8^{tm1d(KOMP)Wtsi} Tg(CAG-RFP,Acr-EGFP)RBGS002Osb/0 involves: C57BL/6 * C57BL/6N * DBA/2	abnormal sperm mitochondrial sheath morphology	J:245977
	absent acrosome	J:245977
	absent sperm mitochondrial sheath	J:245977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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