Kdm8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kdm8
lysine (K)-specific demethylase 8
MGI:1924285

20 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kdm8^{Gt(AZ0518)Wtsi}/Kdm8^{Gt(AZ0518)Wtsi} involves: 129P2/OlaHsd * C57BL/6	abnormal embryo turning	J:182585
	decreased embryo size	J:182585
	embryonic growth retardation	J:182585
	embryonic lethality during organogenesis, complete penetrance	J:182585
	open neural tube	J:182585
Kdm8^tm1.1Tasu/Kdm8^tm1.1Tasu involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:181189
Kdm8^tm1.2Tasu/Kdm8^tm1.2Tasu involves: 129S4/SvJae * C3H * C57BL/6	abnormal visceral yolk sac morphology	J:181189
	absent vitelline blood vessels	J:181189
	embryonic growth retardation	J:181189
	embryonic lethality during organogenesis, complete penetrance	J:181189
	incomplete embryo turning	J:181189
Kdm8^{tm1a(EUCOMM)Wtsi}/Kdm8⁺ C57BL/6N-Kdm8^{tm1a(EUCOMM)Wtsi}/Ics	abnormal glucose homeostasis	J:165965
	abnormal iris pigmentation	J:165965
	abnormal response to tactile stimuli	J:165965
	increased B cell number	J:165965
	increased body weight	J:165965
Kdm8^{tm1b(EUCOMM)Wtsi}/Kdm8⁺ C57BL/6N-Kdm8^{tm1b(EUCOMM)Wtsi}/Ics	abnormal behavior	J:211773
Kdm8^{tm1b(EUCOMM)Wtsi}/Kdm8^{tm1b(EUCOMM)Wtsi} C57BL/6N-Kdm8^{tm1b(EUCOMM)Wtsi}/Ics	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Kdm8^tm1Tasu/Kdm8^tm1Tasu involves: 129S4/SvJae * C57BL/6	decreased cell proliferation	J:181189
	decreased embryo size	J:181189
	embryonic growth retardation	J:181189
	embryonic lethality during organogenesis, incomplete penetrance	J:181189
	prenatal lethality	J:181189
	preweaning lethality, complete penetrance	J:181189

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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