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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atg16l1
autophagy related 16 like 1
MGI:1924290
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Api5em1Cad/Api5+
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Vil1-cre)997Gum/0
involves: C57BL/6J * C57BL/6N * SJL 		abnormal Paneth cell morphology J:340266
decreased Paneth cell number J:340266
Api5em1Cad/Api5em1Cad
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Vil1-cre)997Gum/0
involves: C57BL/6J * C57BL/6N * SJL 		preweaning lethality, incomplete penetrance J:340266
Atg16l1Gt(BC0122)Wtsi/Atg16l1Gt(BC0122)Wtsi
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
involves: 129P2/OlaHsd * C57BL/6NCrj 		impaired autophagy J:181308
Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tcrdtm1Mom/Tcrdtm1Mom
Tg(Vil1-cre)997Gum/0
involves: 129P2/OlaHsd * C57BL/6J * C57BL/6N * SJL 		abnormal cytokine level J:340266
abnormal Paneth cell morphology J:340266
decreased Paneth cell number J:340266
decreased small intestinal villus height J:340266
increased small intestinal crypt cell apoptosis J:340266
increased susceptibility to colitis induced morbidity/mortality J:340266
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Tg(Vil1-cre)997Gum/0
Xbp1tm2Glm/Xbp1tm2Glm
B6.Cg-Atg16l1tm1Kuv Xbp1tm2Glm Tg(Vil1-cre)997Gum 		increased enterocyte apoptosis J:269933
small intestinal inflammation J:269933
Atg16l1tm1Kuv/Atg16l1tm1Kuv
Xbp1tm2Glm/Xbp1tm2Glm
Tg(Vil1-cre)997Gum/0
involves: 129S6/SvEvTac * C57BL/6 * SJL 		abnormal enterocyte physiology J:206084
ileum inflammation J:206084
intestinal inflammation J:206084
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory