Mtmr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mtmr2
myotubularin related protein 2
MGI:1924366

18 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mtmr2^{em1(IMPC)Hmgu}/Mtmr2^{em1(IMPC)Hmgu} C57BL/6NCrl-Mtmr2^{em1(IMPC)Hmgu}/Ieg	decreased startle reflex	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating creatinine level	J:211773
	increased mean platelet volume	J:211773
Mtmr2^tm1.1Abol/Mtmr2^tm1.1Abol involves: 129S2/SvPas	abnormal autopod morphology	J:94373
	abnormal gait	J:94373
	abnormal myelination	J:94373
	abnormal nerve conduction	J:94373
	abnormal sciatic nerve morphology	J:94373
	abnormal spermatogenesis	J:94373
	axon degeneration	J:94373
	decreased body weight	J:94373
	limb grasping	J:94373
	long stride length	J:94373
	prenatal lethality, incomplete penetrance	J:94373
	tremors	J:94373
Mtmr2^tm1Abol/Mtmr2^tm1Abol Tg(Mpz-cre)26Mes/0 involves: 129S2/SvPas * FVB/N	abnormal myelination	J:94373
	abnormal sciatic nerve morphology	J:94373
Mtmr2^tm1Dgen/Mtmr2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679
Mtmr2^tm1Ueli/Mtmr2^tm1Ueli involves: 129S6/SvEvTac * C57BL/6	abnormal myelination	J:104120
	limb grasping	J:104120
	normal nervous system phenotype	J:104120

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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