Coq6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Coq6
coenzyme Q6 monooxygenase
MGI:1924408

35 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Coq6^{tm1a(EUCOMM)Hmgu}/Coq6^{tm1a(EUCOMM)Hmgu} involves: C57BL/6N	embryonic lethality, complete penetrance	J:278754
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ B6N(Cg)-Coq6^{tm1b(EUCOMM)Hmgu}/J	increased circulating sodium level	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6⁺ C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/Ics	abnormal cornea morphology	J:211773
	abnormal vitreous body morphology	J:211773
	increased fasting circulating glucose level	J:211773
	persistence of hyaloid vascular system	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6^{tm1b(EUCOMM)Hmgu} B6N(Cg)-Coq6^{tm1b(EUCOMM)Hmgu}/J	abnormal embryo size	J:211773
	abnormal forebrain development	J:211773
	abnormal tail bud morphology	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Coq6^{tm1b(EUCOMM)Hmgu}/Coq6^{tm1b(EUCOMM)Hmgu} C57BL/6N-Coq6^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Coq6^{tm1c(EUCOMM)Hmgu}/Coq6^{tm1c(EUCOMM)Hmgu} Tg(NPHS2-cre)295Lbh/0 involves: C57BL/6 * C57BL/6N * SJL	abnormal glomerular capillary morphology	J:278754
	abnormal mitochondrial physiology	J:278754
	abnormal podocyte morphology	J:278754
	abnormal podocyte slit junction morphology	J:278754
	albuminuria	J:278754
	decreased podocyte number	J:278754
	dilated renal tubule	J:278754
	disheveled coat	J:278754
	glomerulosclerosis	J:278754
	hunched posture	J:278754
	increased mitochondrial number	J:278754
	increased mitochondrial size	J:278754
	increased renal glomerulus basement membrane thickness	J:278754
	increased urine protein level	J:278754
	moribund	J:278754
	pale kidney	J:278754
	podocyte foot process effacement	J:278754
	premature death	J:278754
	renal cast	J:278754
	renal glomerulus fibrosis	J:278754
	renal interstitial fibrosis	J:278754
	renal tubule atrophy	J:278754
	small kidney	J:278754

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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