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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Notum
notum palmitoleoyl-protein carboxylesterase
MGI:1924833
46 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Notumem1(IMPC)Tcp/Notum+
C57BL/6NCrl-Notumem1(IMPC)Tcp/Tcp 		abnormal cholesterol homeostasis J:211773
abnormal uterus morphology J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
small ovary J:211773
small spleen J:211773
small uterus J:211773
Notumem1(IMPC)Tcp/Notumem1(IMPC)Tcp
C57BL/6NCrl-Notumem1(IMPC)Tcp/Tcp 		abnormal brain morphology J:211773
abnormal kidney morphology J:211773
anophthalmia J:211773
preweaning lethality, incomplete penetrance J:211773
Notumem150Sinn/Notumem150Sinn
Not Specified 		abnormal bronchus morphology J:260471
abnormal kidney development J:260471
abnormal trachea development J:260471
abnormal trachea morphology J:260471
abnormal tracheal cartilage morphology J:260471
abnormal tracheal smooth muscle morphology J:260471
decreased tracheal cartilage ring number J:260471
perinatal lethality J:260471
trachea stenosis J:260471
NotumGt(OST172035)Lex/Notum+
involves: 129S5/SvEvBrd * C57BL/6 		increased bone mineral density J:274615
increased bone strength J:274615
increased compact bone thickness J:274615
NotumGt(OST172035)Lex/NotumGt(OST172035)Lex
involves: 129S5/SvEvBrd * C57BL/6 		abnormal cementum morphology J:266040
abnormal dentin development J:266040
abnormal dentin morphology J:274615
abnormal molar morphology J:274615
abnormal molar root morphology J:266040
abnormal odontoblast morphology J:266040
abnormal periodontal ligament morphology J:266040
anemia J:274615
apical tooth abscess J:266040
carious teeth J:266040
chronic inflammation J:274615
decreased body fat mass J:274615
decreased body weight J:274615
decreased lean body mass J:274615
dental pulp necrosis J:266040
increased bone mineral density J:274615
increased bone strength J:274615
increased compact bone thickness J:274615
increased femur compact bone thickness J:274615
increased kidney weight J:266040
increased lean body mass J:266040
increased leukocyte cell number J:274615
periodontium inflammation J:266040
postnatal lethality, incomplete penetrance J:266040
single kidney J:266040
normal skeleton phenotype J:274615
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory