About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ccdc88a
coiled coil domain containing 88A
MGI:1925177
36 phenotypes from 4 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ccdc88atm1Mat/Ccdc88a+
Not Specified 		abnormal excitatory postsynaptic currents J:217412
abnormal long-term object recognition memory J:217412
impaired contextual conditioning behavior J:217412
impaired spatial learning J:217412
reduced long-term potentiation J:217412
Ccdc88atm1Mat/Ccdc88atm1Mat
Not Specified 		abnormal GABAergic neuron morphology J:173379
abnormal neocortex morphology J:173379
abnormal neuron differentiation J:173379
abnormal neuronal precursor cell migration J:173379
abnormal olfactory bulb development J:173379
abnormal olfactory bulb glomerular layer morphology J:173379
abnormal olfactory bulb granule cell layer morphology J:173379
abnormal olfactory bulb mitral cell layer morphology J:173379
abnormal olfactory bulb morphology J:173379
abnormal olfactory bulb subventricular zone morphology J:173379
abnormal retina vasculature morphology J:145672
abnormal rostral migratory stream morphology J:173379
decreased angiogenesis J:145672
decreased body weight J:145672
decreased brain size J:173379
decreased neuron number J:173379
normal nervous system phenotype J:173379
premature death J:145672
small olfactory bulb J:173379
weight loss J:145672
Ccdc88atm2.1Mat/Ccdc88atm2.1Mat
involves: 129S6/SvEvTac * C57BL/6 		abnormal dendritic spine morphology J:217412
abnormal excitatory postsynaptic currents J:217412
abnormal habituation to a new environment J:217412
decreased prepulse inhibition J:217412
normal growth/size/body region phenotype J:173379
impaired contextual conditioning behavior J:217412
impaired long-term object recognition memory J:217412
impaired spatial learning J:217412
normal mortality/aging J:173379
reduced long-term potentiation J:217412
reduced sensorimotor gating J:217412
Ccdc88atm3.1Mat/Ccdc88atm3.1Mat
involves: 129S6/SvEvTac * C57BL/6 		abnormal neuronal precursor cell migration J:173379
abnormal olfactory bulb development J:173379
abnormal rostral migratory stream morphology J:173379
premature death J:173379
weight loss J:173379
Ccdc88atm4.1Mat/Ccdc88a+
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL 		small olfactory bulb J:190129
Ccdc88atm4.1Mat/Ccdc88atm4.1Mat
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL 		abnormal dentate gyrus morphology J:190129
abnormal rostral migratory stream morphology J:190129
decreased body weight J:190129
decreased locomotor activity J:190129
postnatal growth retardation J:190129
postnatal lethality, complete penetrance J:190129
small olfactory bulb J:190129
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory