Atrip Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atrip
ATR interacting protein
MGI:1925349

29 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal cell physiology	J:299031
	abnormal lens epithelium morphology	J:299031
	abnormal lens fiber morphology	J:299031
	abnormal mitosis	J:299031
	cerebellum hypoplasia	J:299031
	decreased birth weight	J:299031
	decreased body weight	J:299031
	decreased cerebral cortex total cell area	J:299031
	decreased dorsal striatum total cell area	J:299031
	hippocampus hypoplasia	J:299031
	increased lens epithelium apoptosis	J:299031
	microcephaly	J:299031
	microphthalmia	J:299031
	normal mortality/aging	J:299031
	preweaning lethality, complete penetrance	J:299031
Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Pax6-cre,GFP)1Pgr/0 involves: 129P2/OlaHsd * C57BL/6 * FVB * SJL	aphakia	J:299031
	microphthalmia	J:299031
Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Pax6-cre,GFP)2Pgr/0 involves: 129P2/OlaHsd * C57BL/6	abnormal eye physiology	J:297493
	abnormal retina layer morphology	J:297493
	abnormal retina morphology	J:297493
	abnormal retina progenitor cell morphology	J:297493
	decreased visual acuity	J:297493
	increased retina apoptosis	J:297493
	microphthalmia	J:297493
	retina outer nuclear layer degeneration	J:297493
	retina photoreceptor degeneration	J:297493
Atrip^tm1.1Pof/Atrip^tm1.1Pof Tg(Rho-icre)1Ck/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	normal vision/eye phenotype	J:297493
Atrip^{tm1b(KOMP)Wtsi}/Atrip⁺ B6N(Cg)-Atrip^{tm1b(KOMP)Wtsi}/J	decreased fasting circulating glucose level	J:211773
	increased circulating chloride level	J:211773
	increased circulating sodium level	J:211773
Atrip^{tm1b(KOMP)Wtsi}/Atrip^{tm1b(KOMP)Wtsi} B6N(Cg)-Atrip^{tm1b(KOMP)Wtsi}/J	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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