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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atrip
ATR interacting protein
MGI:1925349
29 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atriptm1.1Pof/Atriptm1.1Pof
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal cell physiology J:299031
abnormal lens epithelium morphology J:299031
abnormal lens fiber morphology J:299031
abnormal mitosis J:299031
cerebellum hypoplasia J:299031
decreased birth weight J:299031
decreased body weight J:299031
decreased cerebral cortex total cell area J:299031
decreased dorsal striatum total cell area J:299031
hippocampus hypoplasia J:299031
increased lens epithelium apoptosis J:299031
microcephaly J:299031
microphthalmia J:299031
normal mortality/aging J:299031
preweaning lethality, complete penetrance J:299031
Atriptm1.1Pof/Atriptm1.1Pof
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129P2/OlaHsd * C57BL/6 * FVB * SJL 		aphakia J:299031
microphthalmia J:299031
Atriptm1.1Pof/Atriptm1.1Pof
Tg(Pax6-cre,GFP)2Pgr/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal eye physiology J:297493
abnormal retina layer morphology J:297493
abnormal retina morphology J:297493
abnormal retina progenitor cell morphology J:297493
decreased visual acuity J:297493
increased retina apoptosis J:297493
microphthalmia J:297493
retina outer nuclear layer degeneration J:297493
retina photoreceptor degeneration J:297493
Atriptm1.1Pof/Atriptm1.1Pof
Tg(Rho-icre)1Ck/0
involves: 129P2/OlaHsd * C57BL/6 * SJL 		normal vision/eye phenotype J:297493
Atriptm1b(KOMP)Wtsi/Atrip+
B6N(Cg)-Atriptm1b(KOMP)Wtsi/J 		decreased fasting circulating glucose level J:211773
increased circulating chloride level J:211773
increased circulating sodium level J:211773
Atriptm1b(KOMP)Wtsi/Atriptm1b(KOMP)Wtsi
B6N(Cg)-Atriptm1b(KOMP)Wtsi/J 		embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory