Adgra2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adgra2
adhesion G protein-coupled receptor A2
MGI:1925810

30 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adgra2^tm1.1Bstc/Adgra2^tm1.2Bstc Tg(Tek-cre)12Flv/0 B6.Cg-Adgra2^tm1.1Bstc/Adgra2^tm1.2Bstc Tg(Tek-cre)12Flv	abnormal brain vasculature morphology	J:171226
	abnormal pallium development	J:171226
	abnormal telencephalon development	J:171226
	intracranial hemorrhage	J:171226
	spinal hemorrhage	J:171226
Adgra2^tm1.1Vlcg/Adgra2^tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	abnormal angiogenesis	J:169064
	abnormal blood vessel morphology	J:169064
	abnormal brain vasculature morphology	J:169064
	cleft palate	J:169064
	cleft secondary palate	J:169064
	enlarged lateral ventricles	J:169064
	hemorrhage	J:169064
	megacephaly	J:169064
	normal nervous system phenotype	J:169064
	perinatal lethality, complete penetrance	J:169064
	small lung	J:169064
Adgra2^tm1.1Vlcg/Adgra2^tm2.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671
Adgra2^tm1.1Vlcg/Adgra2^tm2.1Vlcg Gt(ROSA)26Sor^{tm3.1(cre/ERT2)Vlcg}/Gt(ROSA)26Sor⁺ involves: 129S6/SvEvTac * C57BL/6NTac	abnormal brain vasculature morphology	J:200671
Adgra2^tm1.2Bstc/Adgra2^tm1.2Bstc B6.Cg-Adgra2^tm1.2Bstc	abnormal blood vessel morphology	J:171226
	abnormal blood-cerebrospinal fluid barrier function	J:171226
	abnormal brain vasculature morphology	J:171226
	abnormal lateral ventricle morphology	J:171226
	abnormal pallium development	J:171226
	abnormal telencephalon development	J:171226
	abnormal telencephalon morphology	J:171226
	abnormal vascular branching morphogenesis	J:171226
	enlarged lateral ventricles	J:171226
	hydrocephaly	J:171226
	impaired blood-brain barrier function	J:171226
	intracranial hemorrhage	J:171226
	intraventricular hemorrhage	J:171226
	neonatal lethality, complete penetrance	J:171226
	perinatal lethality, complete penetrance	J:171226
	spinal hemorrhage	J:171226
Adgra2^tm1Cjku/Adgra2^tm1Cjku involves: 129	abnormal angiogenesis	J:166127
	abnormal blood vessel morphology	J:166127
	abnormal embryonic/fetal subventricular zone morphology	J:166127
	abnormal nervous system physiology	J:166127
	abnormal neural tube morphology	J:166127
	abnormal perineural vascular plexus morphology	J:166127
	abnormal telencephalon morphology	J:166127
	abnormal vascular branching morphogenesis	J:166127
	internal hemorrhage	J:166127
	lethality throughout fetal growth and development, complete penetrance	J:166127
Adgra2^tm1Cjku/Adgra2^tm2Cjku Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 involves: 129/Sv * C57BL/6 * CBA	abnormal blood vessel morphology	J:166127
	abnormal vascular branching morphogenesis	J:166127
	internal hemorrhage	J:166127
Adgra2^tm1Cjku/Adgra2^tm2Cjku Tg(Tek-cre)12Flv/0 involves: 129/Sv * C3H * C57BL/6	abnormal blood vessel morphology	J:166127
	internal hemorrhage	J:166127
Adgra2^tm2.1Vlcg/Adgra2^tm2.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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