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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fhod3
formin homology 2 domain containing 3
MGI:1925847
29 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fhod3em1(IMPC)Mbp/Fhod3+
C57BL/6N-Fhod3em1(IMPC)Mbp/Ucd 		abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
decreased exploration in new environment J:211773
increased freezing behavior J:211773
Fhod3em1(IMPC)Mbp/Fhod3em1(IMPC)Mbp
C57BL/6N-Fhod3em1(IMPC)Mbp/Ucd 		abnormal forebrain development J:211773
abnormal heart morphology J:211773
abnormal hindbrain development J:211773
abnormal midbrain development J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
embryonic growth retardation J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Fhod3tm1Hsum/Fhod3+
Tg(Myh6-Fhod3*I1127A)#Hsum/0
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj 		abnormal heart development J:187358
abnormal myocardium layer morphology J:187358
dilated heart J:187358
postnatal lethality, complete penetrance J:187358
preweaning lethality, incomplete penetrance J:187358
thin ventricular wall J:187358
Fhod3tm1Hsum/Fhod3tm1Hsum
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj 		abnormal heart development J:187358
abnormal heartbeat J:187358
abnormal myocardial trabeculae morphology J:187358
abnormal vitelline vasculature morphology J:187358
absent heartbeat J:187358
decreased embryo size J:187358
decreased heart ventricle muscle contractility J:187358
delayed heart looping J:187358
embryonic growth retardation J:187358
embryonic lethality during organogenesis, complete penetrance J:187358
pericardial effusion J:187358
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory