Marchf2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Marchf2
membrane associated ring-CH-type finger 2
MGI:1925915

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Marchf2^em1(IMPC)Mbp/Marchf2^em1(IMPC)Mbp C57BL/6NCrl-Marchf2^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	impaired glucose tolerance	J:211773
	increased hemoglobin content	J:211773
Marchf2^em1Cnu/Marchf2^em1Cnu C57BL/6-Marchf2^em1Cnu	decreased susceptibility to bacterial infection	J:297482
	decreased susceptibility to viral infection	J:297482
	increased circulating interferon-beta level	J:297482
	increased circulating interleukin-6 level	J:297482
	increased circulating interleukin-12 level	J:297482
	increased circulating tumor necrosis factor level	J:297482
	increased interleukin-6 secretion	J:297482
	increased interleukin-12 secretion	J:297482
	increased susceptibility to bacterial infection induced morbidity/mortality	J:297482
	increased susceptibility to endotoxin shock	J:297482

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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