Rnf20 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf20
ring finger protein 20
MGI:1925927

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rnf20^{Gt(RRJ249)Byg}/Rnf20⁺ involves: 129P2/OlaHsd	abnormal intestine physiology	J:268221
	abnormal leukocyte physiology	J:268221
	abnormal nitric oxide homeostasis	J:268221
	abnormal T cell physiology	J:268221
	decreased colon length	J:268221
	enlarged spleen	J:268221
	increased colon adenocarcinoma incidence	J:268221
	increased incidence of tumors by chemical induction	J:268221
	increased interferon-gamma secretion	J:268221
	increased large intestine adenocarcinoma incidence	J:268221
	increased myeloid cell number	J:268221
	increased spleen weight	J:268221
	increased susceptibility to induced colitis	J:268221
	increased susceptibility to weight loss	J:268221
	increased tumor necrosis factor secretion	J:268221
	oxidative stress	J:268221
Rnf20^{Gt(RRJ249)Byg}/Rnf20^{Gt(RRJ249)Byg} involves: 129P2/OlaHsd	embryonic lethality before implantation, complete penetrance	J:268221
Rnf20^{tm1.1(KOMP)Vlcg}/Rnf20⁺ C57BL/6N-Rnf20^{tm1.1(KOMP)Vlcg}/Tcp	abnormal behavior	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
Rnf20^{tm1.1(KOMP)Vlcg}/Rnf20^{tm1.1(KOMP)Vlcg} C57BL/6N-Rnf20^{tm1.1(KOMP)Vlcg}/Tcp	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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