Brpf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brpf1
bromodomain and PHD finger containing, 1
MGI:1926033

42 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1⁺ involves: C57BL/6J * C57BL/6N	no abnormal phenotype detected	J:222304
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1⁺ Not Specified	decreased body weight	J:165965
	decreased bone mineral density	J:165965
	decreased T cell number	J:165965
	increased monocyte cell number	J:165965
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	embryonic lethality, complete penetrance	J:222304
Brpf1^{tm1b(EUCOMM)Wtsi}/Brpf1^{tm1b(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal embryo morphology	J:222304
	embryonic growth arrest	J:222304
	embryonic lethality during organogenesis, complete penetrance	J:222304
Brpf1^{tm1c(EUCOMM)Wtsi}/Brpf1^{tm1c(EUCOMM)Wtsi} Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6J * C57BL/6N * C57BL/10 * CBA/Ca	abnormal cell physiology	J:240552
Brpf1^{tm1c(EUCOMM)Wtsi}/Brpf1^{tm1c(EUCOMM)Wtsi} Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * C57BL/6J * C57BL/6N	abnormal behavior	J:241490
	abnormal cell cycle checkpoint function	J:224155
	abnormal cell physiology	J:240552
	abnormal corpus callosum morphology	J:224155
	abnormal dentate gyrus morphology	J:224155
	abnormal hippocampal mossy fiber morphology	J:224155
	abnormal hippocampus CA1 region morphology	J:224155
	abnormal hippocampus development	J:224155
	abnormal hippocampus morphology	J:224155
	abnormal hippocampus neuron morphology	J:224155
	abnormal hippocampus pyramidal cell layer	J:224155
	abnormal hippocampus region morphology	J:224155
	abnormal neocortex morphology	J:224155, J:241490
	abnormal nest building behavior	J:241490
	abnormal neuronal precursor cell migration	J:224155
	abnormal neuronal stem cell morphology	J:224155
	abnormal radial glial cell morphology	J:224155
	decreased body size	J:241490
	decreased corpus callosum size	J:241490
	decreased dentate gyrus size	J:224155
	decreased food intake	J:241490
	decreased neocortex size	J:241490
	decreased neuronal precursor cell number	J:224155
	decreased neuronal precursor proliferation	J:224155, J:241490
	decreased radial glial cell number	J:224155
	increased subiculum size	J:224155
	limb grasping	J:241490
	normal nervous system phenotype	J:241490
	postnatal lethality, incomplete penetrance	J:224155, J:241490
	prenatal growth retardation	J:241490
	prenatal lethality, incomplete penetrance	J:241490
	thin cortical plate	J:241490
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1⁺ involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N	abnormal cell physiology	J:240552
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1^{tm1d(EUCOMM)Wtsi} involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N	abnormal cell physiology	J:240552
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1^{tm1d(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	embryonic lethality during organogenesis, incomplete penetrance	J:222304

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24