Brpf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brpf1
bromodomain and PHD finger containing, 1
MGI:1926033

42 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1⁺ involves: C57BL/6J * C57BL/6N	no abnormal phenotype detected	J:222304
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1⁺ Not Specified	decreased body weight	J:165965
	decreased bone mineral density	J:165965
	decreased T cell number	J:165965
	increased monocyte cell number	J:165965
Brpf1^{tm1a(EUCOMM)Wtsi}/Brpf1^{tm1a(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	embryonic lethality, complete penetrance	J:222304
Brpf1^{tm1b(EUCOMM)Wtsi}/Brpf1^{tm1b(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal embryo morphology	J:222304
	embryonic growth arrest	J:222304
	embryonic lethality during organogenesis, complete penetrance	J:222304
Brpf1^{tm1c(EUCOMM)Wtsi}/Brpf1^{tm1c(EUCOMM)Wtsi} Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6J * C57BL/6N * C57BL/10 * CBA/Ca	abnormal cell physiology	J:240552
Brpf1^{tm1c(EUCOMM)Wtsi}/Brpf1^{tm1c(EUCOMM)Wtsi} Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas * C57BL/6J * C57BL/6N	abnormal behavior	J:241490
	abnormal cell cycle checkpoint function	J:224155
	abnormal cell physiology	J:240552
	abnormal corpus callosum morphology	J:224155
	abnormal dentate gyrus morphology	J:224155
	abnormal hippocampal mossy fiber morphology	J:224155
	abnormal hippocampus CA1 region morphology	J:224155
	abnormal hippocampus development	J:224155
	abnormal hippocampus morphology	J:224155
	abnormal hippocampus neuron morphology	J:224155
	abnormal hippocampus pyramidal cell layer	J:224155
	abnormal hippocampus region morphology	J:224155
	abnormal neocortex morphology	J:224155, J:241490
	abnormal nest building behavior	J:241490
	abnormal neuronal precursor cell migration	J:224155
	abnormal neuronal stem cell morphology	J:224155
	abnormal radial glial cell morphology	J:224155
	decreased body size	J:241490
	decreased corpus callosum size	J:241490
	decreased dentate gyrus size	J:224155
	decreased food intake	J:241490
	decreased neocortex size	J:241490
	decreased neuronal precursor cell number	J:224155
	decreased neuronal precursor proliferation	J:224155, J:241490
	decreased radial glial cell number	J:224155
	increased subiculum size	J:224155
	limb grasping	J:241490
	normal nervous system phenotype	J:241490
	postnatal lethality, incomplete penetrance	J:224155, J:241490
	prenatal growth retardation	J:241490
	prenatal lethality, incomplete penetrance	J:241490
	thin cortical plate	J:241490
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1⁺ involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N	abnormal cell physiology	J:240552
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1^{tm1d(EUCOMM)Wtsi} involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N	abnormal cell physiology	J:240552
Brpf1^{tm1d(EUCOMM)Wtsi}/Brpf1^{tm1d(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	embryonic lethality during organogenesis, incomplete penetrance	J:222304

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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