About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nckap1l
NCK associated protein 1 like
MGI:1926063
57 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Nckap1lm1Btlr/Nckap1lm1Btlr
C57BL/6J-Nckap1lm1Btlr 		decreased alpha-beta T cell number J:272079
decreased B cell number J:272079
decreased body weight J:272079
decreased CD4-positive, alpha-beta T cell number J:272079
decreased CD8-positive, alpha-beta T cell number J:272079
decreased CD8-positive, naive alpha-beta T cell number J:272079
decreased central memory CD8 positive, alpha-beta T cell number J:272079
decreased NK cell number J:272079
increased alpha-beta T cell number J:272079
increased CD8-positive, alpha-beta T cell number J:272079
increased effector memory CD4-positive, alpha-beta T cell number J:272079
increased effector memory CD8-positive, alpha-beta T cell number J:272079
Nckap1lm1Iri/Nckap1lm1Iri
involves: C57BL/6 		abnormal CD4-positive T cell differentiation J:141377
abnormal common myeloid progenitor cell morphology J:141377
abnormal epididymis morphology J:141377
abnormal erythroid progenitor cell morphology J:141377
abnormal immune system organ morphology J:141377
abnormal liver morphology J:141377
abnormal lymphopoiesis J:141377
abnormal regulatory T cell number J:141377
abnormal renal glomerulus morphology J:141377
abnormal thoracic cavity morphology J:141377
abnormal thymus lobule morphology J:141377
acanthocytosis J:141377
amyloidosis J:141377
cardiac fibrosis J:141377
dacryocytosis J:141377
decreased CD4-positive, alpha-beta T cell number J:141377
decreased CD8-positive, alpha-beta T cell number J:141377
decreased double-positive T cell number J:141377
decreased hematocrit J:141377
decreased lymphocyte cell number J:141377
decreased mature B cell number J:141377
decreased mature gamma-delta T cell number J:141377
decreased mean corpuscular volume J:141377
decreased T cell proliferation J:141377
extramedullary hematopoiesis J:141377
heart inflammation J:141377
hypochromic microcytic anemia J:141377
impaired macrophage phagocytosis J:141377
impaired neutrophil chemotaxis J:141377
impaired neutrophil phagocytosis J:141377
increased circulating interleukin-6 level J:141377
increased circulating interleukin-17 level J:141377
increased double-negative T cell number J:141377
increased erythrocyte osmotic fragility J:141377
increased interleukin-6 secretion J:141377
increased interleukin-17 secretion J:141377
increased leukocyte cell number J:141377
increased neutrophil cell number J:141377
increased tumor necrosis factor secretion J:141377
liver inflammation J:141377
lung inflammation J:141377
lymph node hypoplasia J:141377
poikilocytosis J:141377
reticulocytosis J:141377
schistocytosis J:141377
spleen hyperplasia J:141377
thymus hypoplasia J:141377
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory