Abraxas2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abraxas2
BRISC complex subunit
MGI:1926116

15 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Abraxas2^tm1.2Bwng/Abraxas2⁺ involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl	enlarged spleen	J:245949
	increased lung adenocarcinoma incidence	J:245949
	increased lymphoma incidence	J:245949
	increased tumor incidence	J:245949
	premature death	J:245949
Abraxas2^tm1.2Bwng/Abraxas2^tm1.2Bwng involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl	abnormal cell nucleus morphology	J:245949
	abnormal chromosome morphology	J:245949
	abnormal DNA replication	J:245949
	abnormal mitosis	J:245949
	normal cellular phenotype	J:245949
	chromosomal instability	J:245949
	enlarged spleen	J:245949
	increased cellular sensitivity to DNA damaging agents	J:245949
	increased cellular sensitivity to ultraviolet irradiation	J:245949
	increased inflammatory response	J:245949
	increased lung adenocarcinoma incidence	J:245949
	increased lymphoma incidence	J:245949
	increased sebaceous gland tumor incidence	J:245949
	increased tumor incidence	J:245949
	premature death	J:245949

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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