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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Arid1b
AT-rich interaction domain 1B
MGI:1926129
55 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arid1bem1(IMPC)Tcp/Arid1b+
C57BL/6NCrl-Arid1bem1(IMPC)Tcp/Tcp 		abnormal freezing behavior J:211773
abnormal spleen morphology J:211773
decreased exploration in new environment J:211773
decreased fasting circulating glucose level J:211773
decreased locomotor activity J:211773
decreased prepulse inhibition J:211773
impaired cued conditioning behavior J:211773
increased circulating creatinine level J:211773
increased freezing behavior J:211773
Arid1bem1(IMPC)Tcp/Arid1bem1(IMPC)Tcp
C57BL/6NCrl-Arid1bem1(IMPC)Tcp/Tcp 		edema J:211773
preweaning lethality, complete penetrance J:211773
Arid1bem1Hzhu/Arid1b+
C57BL/6J-Arid1bem1Hzhu 		abnormal dentate gyrus subgranular zone morphology J:256668
abnormal homeostasis J:256668
abnormal hypothalamus physiology J:256668
abnormal insulin-like growth factor I level J:256668
abnormal response to social novelty J:256668
abnormal vocalization J:256668
normal behavior/neurological phenotype J:256668
decreased body length J:256668
decreased body size J:256668
decreased body weight J:256668
decreased cerebral cortex cell number J:256668
decreased circulating insulin-like growth factor I level J:256668
decreased corpus callosum size J:256668
decreased dentate gyrus size J:256668
decreased grip strength J:256668
decreased heart weight J:256668
decreased kidney weight J:256668
decreased neuron number J:256668
hydrocephaly J:256668
increased anxiety-related response J:256668
increased grooming behavior J:256668
muscle weakness J:256668
postnatal growth retardation J:256668
small heart J:256668
small kidney J:256668
thin cerebral cortex J:256668
Arid1bem1Hzhu/Arid1bem1Hzhu
C57BL/6J-Arid1bem1Hzhu 		decreased birth body size J:256668
perinatal lethality, complete penetrance J:256668
Arid1bem1Iha/Arid1b+
C57BL/6J-Arid1bem1Iha 		abnormal brain vasculature morphology J:271850
abnormal hippocampus pyramidal cell layer J:271850
abnormal long-term spatial reference memory J:271850
abnormal social investigation J:271850
cognitive inflexibility J:271850
decreased body weight J:271850
decreased exploration in new environment J:271850
decreased grip strength J:271850
decreased prepulse inhibition J:271850
decreased startle reflex J:271850
enhanced cued conditioning behavior J:271850
enlarged lateral ventricles J:271850
hydrocephaly J:271850
impaired coordination J:271850
increased anxiety-related response J:271850
increased fear-related response J:271850
increased stereotypic behavior J:271850
increased thermal nociceptive threshold J:271850
slow extinction of fear memory J:271850
Arid1bem1Iha/Arid1bem1Iha
C57BL/6J-Arid1bem1Iha 		lethality, complete penetrance J:271850
Arid1btm1b(EUCOMM)Hmgu/Arid1btm1b(EUCOMM)Hmgu
C57BL/6N-Arid1btm1b(EUCOMM)Hmgu/Wtsi 		male infertility J:211773
preweaning lethality, incomplete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory