Sp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sp2
Sp2 transcription factor
MGI:1926162

28 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sp2^tm1.1Htg/Sp2⁺ Tg(Nes-cre)1Kln/0 involves: 129 * C57BL/6 * SJL	abnormal cerebral hemisphere morphology	J:194076
	abnormal rostral migratory stream morphology	J:194076
	decreased body size	J:194076
	decreased hippocampus volume	J:194076
	decreased neuronal precursor proliferation	J:194076
	postnatal growth retardation	J:194076
	small olfactory bulb	J:194076
Sp2^tm1.1Htg/Sp2^tm1.1Htg involves: 129	abnormal cell cycle	J:194076
Sp2^tm1.1Htg/Sp2^tm1.1Htg Emx1^tm1(cre)Krj/Emx1⁺ involves: 129S2/SvPas	abnormal cortical plate morphology	J:194076
	abnormal cortical ventricular zone morphology	J:194076
	abnormal embryonic/fetal subventricular zone morphology	J:194076
	abnormal neuron differentiation	J:194076
	prenatal lethality, incomplete penetrance	J:194076
Sp2^tm1.1Htg/Sp2^tm1.1Htg Tg(Nes-cre)1Kln/0 involves: 129 * C57BL/6 * SJL	abnormal cell cycle	J:194076
	abnormal cerebral hemisphere morphology	J:194076
	abnormal neuron differentiation	J:194076
	abnormal rostral migratory stream morphology	J:194076
	decreased body size	J:194076
	decreased hippocampus volume	J:194076
	decreased neuronal precursor proliferation	J:194076
	hydrocephaly	J:194076
	postnatal growth retardation	J:194076
	postnatal lethality, incomplete penetrance	J:194076
	premature death	J:194076
	small olfactory bulb	J:194076
Sp2^tm1.1Sus/Sp2^tm1.1Sus involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:158671
Sp2^tm1.2Sus/Sp2^tm1.2Sus involves: 129P2/OlaHsd * C57BL/6	abnormal embryo turning	J:158671
	absent fibroblast proliferation	J:158671
	decreased embryo size	J:158671
	embryonic growth retardation	J:158671
	embryonic lethality during organogenesis, complete penetrance	J:158671
	open neural tube	J:158671
Sp2^tm1Sus/Sp2^tm1Sus involves: 129P2/OlaHsd * C57BL/6	decreased fetal size	J:158671
	fetal growth retardation	J:158671
	hemorrhage	J:158671
	lethality throughout fetal growth and development, incomplete penetrance	J:158671
	postnatal lethality, complete penetrance	J:158671

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24