Rbfox1 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
MGI:1926224

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rbfox1^tm1.1Dblk/Rbfox1⁺ Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL	increased susceptibility to pharmacologically induced seizures	J:176189
	increased susceptibility to xenobiotic induced morbidity/mortality	J:176189
Rbfox1^tm1.1Dblk/Rbfox1^tm1.1Dblk Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL	abnormal excitatory postsynaptic potential	J:176189
	decreased body size	J:176189
	decreased dendritic spine density	J:176189
	increased susceptibility to pharmacologically induced seizures	J:176189
	increased susceptibility to xenobiotic induced morbidity/mortality	J:176189
	normal nervous system phenotype	J:176189
	reduced fertility	J:176189
	seizures	J:176189
	tonic-clonic seizures	J:176189
Rbfox1^{tm1b(KOMP)Wtsi}/Rbfox1⁺ C57BL/6N-Rbfox1^{tm1b(KOMP)Wtsi}/Ics	short tibia	J:211773
Rbfox1^{tm1b(KOMP)Wtsi}/Rbfox1^{tm1b(KOMP)Wtsi} C57BL/6N-Rbfox1^{tm1b(KOMP)Wtsi}/Ics	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24