Rbfox1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
MGI:1926224

11 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rbfox1^tm1.1Dblk/Rbfox1⁺ Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL	increased susceptibility to pharmacologically induced seizures	J:176189
	increased susceptibility to xenobiotic induced morbidity/mortality	J:176189
Rbfox1^tm1.1Dblk/Rbfox1^tm1.1Dblk Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL	abnormal excitatory postsynaptic potential	J:176189
	decreased body size	J:176189
	decreased dendritic spine density	J:176189
	increased susceptibility to pharmacologically induced seizures	J:176189
	increased susceptibility to xenobiotic induced morbidity/mortality	J:176189
	normal nervous system phenotype	J:176189
	reduced fertility	J:176189
	seizures	J:176189
	tonic-clonic seizures	J:176189
Rbfox1^{tm1b(KOMP)Wtsi}/Rbfox1⁺ C57BL/6N-Rbfox1^{tm1b(KOMP)Wtsi}/Ics	short tibia	J:211773
Rbfox1^{tm1b(KOMP)Wtsi}/Rbfox1^{tm1b(KOMP)Wtsi} C57BL/6N-Rbfox1^{tm1b(KOMP)Wtsi}/Ics	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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