Rassf5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rassf5
Ras association (RalGDS/AF-6) domain family member 5
MGI:1926375

30 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rassf5^tm1Kina/Rassf5⁺ involves: C57BL/6 * CBA * ICR	lymphoid hypoplasia	J:92670
Rassf5^tm1Kina/Rassf5^tm1Kina B6.Cg-Rassf5^tm1Kina	abnormal lymphocyte physiology	J:168749
	enlarged lymph nodes	J:168749
	enlarged spleen	J:168749
	glomerulonephritis	J:168749
	increased anti-double stranded DNA antibody level	J:168749
	increased B cell derived lymphoma incidence	J:168749
	increased B cell number	J:168749
	increased B cell proliferation	J:168749
	increased hepatocellular carcinoma incidence	J:168749
	increased IgG level	J:168749
	increased lung adenocarcinoma incidence	J:168749
	increased memory T cell number	J:168749
	increased plasma cell number	J:168749
	increased T cell number	J:168749
	increased T cell proliferation	J:168749
	increased urine protein level	J:168749
Rassf5^tm1Kina/Rassf5^tm1Kina involves: C57BL/6 * CBA * ICR	abnormal B cell differentiation	J:92670
	abnormal dendritic cell physiology	J:92670
	abnormal leukocyte migration	J:92670
	abnormal lymph node cell ratio	J:92670
	abnormal lymph node cortex morphology	J:92670
	abnormal spleen red pulp morphology	J:92670
	abnormal thymus cell ratio	J:92670
	abnormal thymus corticomedullary boundary morphology	J:92670
	abnormal thymus medulla morphology	J:92670
	decreased thymocyte number	J:92670
	spleen hypoplasia	J:92670
Rassf5^tm1Sblee/Rassf5^tm1Sblee involves: 129S6/SvEvTac * C57BL/6J	decreased fibroblast apoptosis	J:166871
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:166871

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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