Huwe1 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Huwe1
HECT, UBA and WWE domain containing 1
MGI:1926884

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Huwe1^tm1.1Mak/Y Trp53^tm1Brn/Trp53^tm1Brn involves: 129P2/OlaHsd * C57BL/6 * SJL	abnormal class switch recombination	J:181705
	absent B-1a cells	J:181705
	decreased IgG1 level	J:181705
	decreased IgM level	J:181705
	normal immune system phenotype	J:181705
Huwe1^tm1Wgu/Y Tg(Ins2-cre)23Herr/0 Trp53^tm1Thl/Trp53^tm1Thl involves: C57BL/6J * CBA/J	normal endocrine/exocrine gland phenotype	J:182446
	normal homeostasis/metabolism phenotype	J:182446
	hyperglycemia	J:182446
	normal mortality/aging	J:182446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24