Ube4b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ube4b
ubiquitination factor E4B
MGI:1927086

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Nes-cre)1Kln/0 Ube4b^em1Bcgen/Ube4b^em1Bcgen involves: C57BL/6N * SJL	abnormal brain morphology	J:332423
	abnormal dendrite arborization pattern	J:332423
	decreased body weight	J:332423
	decreased neuronal precursor proliferation	J:332423
	postnatal lethality, incomplete penetrance	J:332423
	tonic-clonic seizures	J:332423
Ube4b^tm1Kei/Ube4b⁺ involves: C57BL/6	abnormal gait	J:103761
	abnormal medulla oblongata morphology	J:103761
	abnormal Purkinje cell morphology	J:103761
	axonal dystrophy	J:103761
	impaired coordination	J:103761
	Purkinje cell degeneration	J:103761
Ube4b^tm1Kei/Ube4b^tm1Kei involves: C57BL/6	abnormal cell physiology	J:103761
	abnormal myocardial fiber morphology	J:103761
	abnormal myocardial trabeculae morphology	J:103761
	abnormal myocardium layer morphology	J:103761
	abnormal vein morphology	J:103761
	congestive heart failure	J:103761
	enlarged heart	J:103761
	hemorrhage	J:103761
	increased cardiomyocyte apoptosis	J:103761
	intraventricular hemorrhage	J:103761
	lethality throughout fetal growth and development, complete penetrance	J:103761
	pericardial edema	J:103761
	pericardial effusion	J:103761

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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