Slc5a7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc5a7
solute carrier family 5 (choline transporter), member 7
MGI:1927126

28 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc5a7^{tm1a(KOMP)Wtsi}/Slc5a7⁺ C57BL/6N-Slc5a7^{tm1a(KOMP)Wtsi}/Wtsi	abnormal hair growth	J:211773
	decreased circulating fructosamine level	J:211773
	decreased total body fat amount	J:211773
	increased grip strength	J:211773
Slc5a7^{tm1a(KOMP)Wtsi}/Slc5a7^{tm1a(KOMP)Wtsi} C57BL/6N-Slc5a7^{tm1a(KOMP)Wtsi}/Wtsi	abnormal coronary sinus connection	J:239583
	abnormal eye morphology	J:239583
	abnormal small intestine morphology	J:239583
	abnormal vertebral artery topology	J:239583
	bicuspid aortic valve	J:239583
	blood in lymph vessels	J:239583
	dilated pancreatic duct	J:239583
	herniated liver	J:239583
	muscular ventricular septal defect	J:239583
	no abnormal phenotype detected	J:239583
	preweaning lethality, complete penetrance	J:211773
	retrolental blood	J:239583
Slc5a7^tm1Rbl/Slc5a7⁺ involves: 129S6/SvEvTac * C57BL/6	increased susceptibility to xenobiotic induced morbidity/mortality	J:90846
Slc5a7^tm1Rbl/Slc5a7^tm1Rbl involves: 129S6/SvEvTac * C57BL/6	abnormal motor neuron innervation pattern	J:90846
	abnormal neuromuscular synapse morphology	J:90846
	abnormal synaptic acetylcholine release	J:90846
	cyanosis	J:90846
	hyporesponsive to tactile stimuli	J:90846
	neonatal lethality, incomplete penetrance	J:90846
	respiratory failure	J:90846
Tg(Slc5a7)1Rbl/? involves: C57BL/6J	enhanced exercise endurance	J:228637
	increased acetylcholine level	J:228637
	increased anxiety-related response	J:228637
	increased locomotor activity	J:228637

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24