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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Syne1
spectrin repeat containing, nuclear envelope 1
MGI:1927152
30 phenotypes from 5 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Syne1em1(IMPC)Bay/Syne1em1(IMPC)Bay
C57BL/6N-Syne1em1(IMPC)Bay/BayMmucd 		preweaning lethality, incomplete penetrance J:211773
Syne1tm1.1Chen/Syne1tm1.1Chen
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss 		abnormal muscle physiology J:155342
abnormal skeletal muscle fiber morphology J:155342
absent gastric milk in neonates J:155342
normal cardiovascular system phenotype J:155342
centrally nucleated skeletal muscle fibers J:155342
decreased body weight J:155342
impaired exercise endurance J:155342
postnatal growth retardation J:155342
postnatal lethality, incomplete penetrance J:155342
weakness J:155342
Syne1tm1.1Mcn/Syne1tm1.1Mcn
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL 		atelectasis J:144757
conjunctivitis J:144757
cyanosis J:144757
decreased birth body size J:144757
decreased body weight J:144757
decreased heart rate J:144757
decreased survivor rate J:144757
dystrophic muscle J:144757
impaired coordination J:144757
kyphoscoliosis J:144757
neonatal lethality, incomplete penetrance J:144757
paraparesis J:144757
poor grooming J:144757
prolonged PR interval J:144757
prolonged QRS complex duration J:144757
prolonged QT interval J:144757
small lung J:144757
Syne1tm1Chen/Syne1tm1Chen
Tg(Nkx2-5-cre)9Eno/?
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * Black Swiss 		abnormal cell nucleus morphology J:211007
Syne1tm1Rexu/Syne1tm1Rexu
involves: 129 * C57BL/6 		abnormal muscle fiber morphology J:118671
abnormal neuromuscular synapse morphology J:118671
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory