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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mettl3
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
MGI:1927165
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mettl3em1Chhe/Mettl3em1Chhe
Mettl14em1Chhe/Mettl14em1Chhe
Stra8em1(GFP/cre)Smoc/Stra8+
involves: C57BL/6J 		abnormal epigenetic regulation of gene expression J:250428
abnormal seminiferous tubule morphology J:250428
abnormal sperm head morphology J:250428
abnormal spermatid morphology J:250428
abnormal translation J:250428
arrest of spermiogenesis J:250428
asthenozoospermia J:250428
decreased sperm progressive motility J:250428
decreased testis weight J:250428
oligozoospermia J:250428
small testis J:250428
teratozoospermia J:250428
Mettl3em1Chhe/Mettl3em1Chhe
Mettl14em1Chhe/Mettl14em1Chhe
Tg(Ddx4-cre)1Dcas/0
involves: C57BL/6J * FVB 		abnormal spermatogonia morphology J:250428
decreased male germ cell number J:250428
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory