Shoc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shoc2
Shoc2, leucine rich repeat scaffold protein
MGI:1927197

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Shoc2^tm1.1Mhan/Shoc2^tm1.1Mhan involves: 129S6/SvEvTac * C57BL/6 * SJL	no abnormal phenotype detected	J:161211
Shoc2^tm1.1Mhan/Shoc2^tm1.2Mhan Tg(Tek-cre)#Xya/0 involves: 129S6/SvEvTac * BALB/c * C57BL/6 * Kunming	abnormal atrioventricular valve development	J:161211
	abnormal cardiac epithelial to mesenchymal transition	J:161211
	abnormal cardiovascular development	J:161211
	abnormal semilunar valve development	J:161211
	normal cardiovascular system phenotype	J:161211
	decreased atrioventricular cushion size	J:161211
	double outlet right ventricle	J:161211
	normal embryo phenotype	J:161211
	embryonic growth retardation	J:161211
	embryonic lethality during organogenesis, incomplete penetrance	J:161211
	hemorrhage	J:161211
	lethality throughout fetal growth and development, complete penetrance	J:161211
	pulmonary vascular congestion	J:161211
	right aortic arch	J:161211
	skin edema	J:161211
	transposition of great arteries	J:161211
	ventricular septal defect	J:161211
Shoc2^tm1.2Mhan/Shoc2^tm1.2Mhan involves: 129S6/SvEvTac * BALB/c * C57BL/6	embryonic lethality, complete penetrance	J:161211

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