Zbtb21 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zbtb21
zinc finger and BTB domain containing 21
MGI:1927240

11 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{em1(CAG-Zbtb21,-GFP)Jhan}/Gt(ROSA)26Sor⁺ Tg(Nes-cre)1Kln/0 B6.Cg-Gt(ROSA)26Sor^{em1(CAG-Zbtb21,-GFP)Jhan} Tg(Nes-cre)1Kln	abnormal CNS synaptic transmission	J:351206
	abnormal excitatory postsynaptic potential	J:351206
	abnormal postsynaptic density morphology	J:351206
	abnormal spatial reference memory	J:351206
	decreased dendritic spine density	J:351206
	impaired contextual conditioning behavior	J:351206
	impaired spatial learning	J:351206
	reduced long-term potentiation	J:351206
Gt(ROSA)26Sor^{em1(CAG-Zbtb21,-GFP)Jhan}/Gt(ROSA)26Sor⁺ Tg(Camk2a-cre)T29-1Stl/0 B6.Cg-Gt(ROSA)26Sor^{em1(CAG-Zbtb21,-GFP)Jhan} Tg(Camk2a-cre)T29-1Stl	abnormal CNS synaptic transmission	J:351206
	abnormal excitatory postsynaptic potential	J:351206
	abnormal spatial reference memory	J:351206
	decreased dendritic spine density	J:351206
	impaired spatial learning	J:351206
	reduced long-term potentiation	J:351206
Gt(ROSA)26Sor^{em1(CAG-Zbtb21,-GFP)Jhan}/Gt(ROSA)26Sor⁺ Aldh1l1^{em1(cre/ERT2)Nju}/Aldh1l1⁺ Not Specified	normal behavior/neurological phenotype	J:351206
	normal nervous system phenotype	J:351206
Zbtb21^em1Jhan/Zbtb21^em1Jhan C57BL/6J-Zbtb21^em1Jhan	normal behavior/neurological phenotype	J:351206
	normal growth/size/body region phenotype	J:351206
	normal nervous system phenotype	J:351206

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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