Xrcc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
MGI:1927345

20 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xrcc2^tm1Jtk/Xrcc2^tm1Jtk involves: 129S/SvEv * C57BL/6	abnormal craniofacial morphology	J:66529
	abnormal developmental patterning	J:66529
	abnormal neural tube closure	J:66529
	abnormal pulmonary alveolus morphology	J:66529
	chromosomal instability	J:66529
	cyanosis	J:66529
	decreased embryo size	J:66529
	embryonic growth retardation	J:66529
	embryonic lethality during organogenesis, incomplete penetrance	J:66529
	exencephaly	J:66529
	increased apoptosis	J:66529
	increased cellular sensitivity to gamma-irradiation	J:66529
	increased embryonic tissue cell apoptosis	J:66529
	increased neuron apoptosis	J:66529
	neonatal lethality, complete penetrance	J:66529
	respiratory failure	J:66529
	short tail	J:66529
	thin cortical plate	J:66529
Xrcc2^tm1Pmc/Xrcc2^tm1Pmc involves: 129S1/Sv * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:111068
Xrcc2^tm1Pmc/Xrcc2^tm1Pmc involves: 129S1/Sv * C57BL/6	increased apoptosis	J:111068
Xrcc2^tm2Pmc/Xrcc2^tm2Pmc Tg(Nes-cre)1Kln/0 involves: 129S1/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:144617

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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