Pdlim5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdlim5
PDZ and LIM domain 5
MGI:1927489

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdlim5^Gt(XH199)Byg/Pdlim5⁺ B6.129P2-Pdlim5^Gt(XH199)Byg	abnormal prepulse inhibition	J:200039
	normal behavior/neurological phenotype	J:200039
	behavioral despair	J:200039
	decreased locomotor activity	J:200039
	impaired behavioral response to addictive substance	J:200039
Pdlim5^Gt(XH199)Byg/Pdlim5^Gt(XH199)Byg B6.129P2-Pdlim5^Gt(XH199)Byg	decreased survivor rate	J:200039
Pdlim5^tm1.1Chen/Pdlim5^tm1.1Chen involves: 129S1/Sv * 129X1/SvJ * Black Swiss	abnormal blood pressure regulation	J:175042
	abnormal cardiac muscle contractility	J:175042
	abnormal cardiovascular system physiology	J:175042
	abnormal heart morphology	J:175042
	abnormal Z line morphology	J:175042
	decreased left ventricle systolic pressure	J:175042
	dilated cardiomyopathy	J:175042
	dilated heart left ventricle	J:175042
	increased heart left ventricle size	J:175042
	increased heart weight	J:175042
	normal mortality/aging	J:175042
	normal reproductive system phenotype	J:175042
Pdlim5^tm1Chen/Pdlim5^tm1Chen Tg(Tnnt2-cre)5Blh/? involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA/2	decreased heart left ventricle muscle contractility	J:175042
	dilated cardiomyopathy	J:175042
	dilated heart left ventricle	J:175042

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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