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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc4a4
solute carrier family 4 (anion exchanger), member 4
MGI:1927555
63 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc4a4tm1.1Slin/Slc4a4+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		acidemia J:186877
acidosis J:186877
Slc4a4tm1.1Slin/Slc4a4tm1.1Slin
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal blood circulation J:186877
abnormal blood homeostasis J:186877
abnormal compact bone morphology J:186877
abnormal intestine morphology J:186877
abnormal intestine physiology J:186877
abnormal renal reabsorption J:186877
abnormal renal tubule epithelium morphology J:186877
abnormal skeleton morphology J:186877
abnormal urine homeostasis J:186877
acidemia J:186877
acidosis J:186877
anemia J:186877
cornea opacity J:186877
decreased body size J:186877
decreased gastrocnemius weight J:186877
decreased hemoglobin content J:186877
decreased kidney weight J:186877
decreased length of long bones J:186877
decreased urine osmolality J:186877
decreased urine pH J:186877
dilated renal tubule J:186877
edema J:186877
enlarged spleen J:186877
increased circulating aldosterone level J:186877
increased circulating calcium level J:186877
increased circulating renin level J:186877
increased long bone epiphyseal plate size J:186877
increased spleen weight J:186877
increased urine calcium level J:186877
increased urine sodium level J:186877
metabolic acidosis J:186877
postnatal growth retardation J:186877
postnatal lethality, complete penetrance J:186877
renal tubular acidosis J:186877
renal tubule atrophy J:186877
reticulocytosis J:186877
uremia J:186877
Slc4a4tm1Ges/Slc4a4+
involves: 129S6/SvEvTac * Black Swiss 		abnormal ammonia homeostasis J:279694
decreased circulating bicarbonate level J:120867, J:279694
decreased urine ammonia level J:279694
decreased urine pH J:279694
normal homeostasis/metabolism phenotype J:279694
metabolic acidosis J:279694
Slc4a4tm1Ges/Slc4a4tm1Ges
involves: 129S6/SvEvTac * Black Swiss 		abnormal ammonia homeostasis J:279694
abnormal cranium morphology J:120867
abnormal ion homeostasis J:120867
abnormal megakaryocyte morphology J:120867
acidosis J:120867
brittle teeth J:120867
cachexia J:120867
coiled cecum J:120867
constipation J:120867
decreased birth body size J:120867
decreased body weight J:120867
decreased circulating bicarbonate level J:120867, J:279694
decreased circulating sodium level J:120867
decreased hematocrit J:120867
decreased lymphocyte cell number J:120867
decreased urine ammonia level J:279694
decreased urine pH J:279694
dilated kidney collecting duct J:279694
disorganized spleen B cell follicle J:120867
enlarged spleen J:120867
normal homeostasis/metabolism phenotype J:279694
increased circulating aldosterone level J:120867
increased nucleated erythrocyte cell number J:120867
increased spleen red pulp amount J:120867
increased spleen white pulp amount J:120867
intestinal obstruction J:120867
metabolic acidosis J:279694
normal nervous system phenotype J:120867
pallor J:120867
postnatal growth retardation J:120867
postnatal lethality, complete penetrance J:120867
small cecum J:120867
normal vision/eye phenotype J:120867
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory