About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Smpd3
sphingomyelin phosphodiesterase 3, neutral
MGI:1927578
70 phenotypes from 2 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Smpd3fro/Smpd3fro
B6N.Cg-Smpd3fro 		postnatal lethality, incomplete penetrance J:193949
Smpd3fro/Smpd3fro
C3H.Cg-Smpd3fro 		postnatal lethality, incomplete penetrance J:193949
Smpd3fro/Smpd3fro
involves: C3H/HeN * C57BL/6N 		abnormal limb morphology J:193949
abnormal lipid level J:193949
abnormal pulmonary alveolus morphology J:193949
emphysema J:193949
increased lung compliance J:193949
overexpanded pulmonary alveolus J:193949
postnatal lethality, incomplete penetrance J:193949
Smpd3fro/Smpd3fro
Not Specified 		abnormal alveolar process morphology J:100158
abnormal bone mineralization J:7673, J:100158
abnormal bone ossification J:3906
abnormal cartilage development J:7673
abnormal clavicle morphology J:3906
abnormal dentin development J:100158
abnormal epiphyseal plate morphology J:3906
abnormal femur morphology J:3906
abnormal fibula morphology J:3906
abnormal humerus morphology J:3906
abnormal ischium morphology J:3906
abnormal limb bone morphology J:3906
abnormal limb morphology J:6711
abnormal long bone metaphysis morphology J:3906
abnormal long bone morphology J:3906, J:6711, J:100158
abnormal olecranon morphology J:3906
abnormal osteoblast morphology J:3906
abnormal perichondrium morphology J:3906
abnormal periosteum morphology J:3906
abnormal pubis morphology J:3906
abnormal rib morphology J:3906
abnormal scapula morphology J:3906
abnormal sternum ossification J:3906
abnormal tibia morphology J:3906
bowed humerus J:3906
bowed radius J:3906
bowed tibia J:3906
bowed ulna J:3906
cyanosis J:3906
decreased body length J:3906
decreased body size J:6711, J:100158
decreased bone mineral density J:3906
decreased bone trabecula number J:3906
decreased length of long bones J:6711
decreased survivor rate J:3906, J:6711
delayed bone ossification J:3906
increased circulating parathyroid hormone level J:7673, J:100158
increased width of hypertrophic chondrocyte zone J:3906
postnatal lethality, incomplete penetrance J:3906, J:6711
reduced fertility J:3906
respiratory distress J:3906
rib fractures J:100158
short femur J:3906
short humerus J:3906
short ribs J:3906
short ulna J:3906
Smpd3tm1Wst/Smpd3tm1Wst
involves: 129S1/Sv 		abnormal adenohypophysis morphology J:97284
abnormal femur morphology J:97284
abnormal fibula morphology J:97284
abnormal long bone morphology J:97284
abnormal ovary development J:97284
abnormal pituicyte morphology J:97284
abnormal spermatogenesis J:97284
abnormal testis development J:97284
abnormal tibia morphology J:97284
decreased body height J:97284
decreased circulating cortisol level J:97284
decreased circulating insulin-like growth factor I level J:97284
decreased corticotroph cell number J:97284
decreased gonadotroph cell number J:97284
decreased primordial ovarian follicle number J:97284
decreased somatotroph cell number J:97284
decreased thyrotroph cell number J:97284
decreased thyroxine level J:97284
decreased triiodothyronine level J:97284
decreased width of hypertrophic chondrocyte zone J:97284
delayed bone ossification J:97284
delayed sexual maturation J:97284
disproportionate dwarf J:97284
fetal growth retardation J:97284
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory